ID   HMT-3909S13
AC   CVCL_UW65
SY   HMT3909S13; HMT-3909/S13; HMT-3909 subline S13
DR   cancercelllines; CVCL_UW65
DR   Wikidata; Q94213575
RX   PubMed=11801722;
RX   PubMed=16807805;
RX   PubMed=22692575;
CC   Group: Triple negative breast cancer (TNBC) cell line.
CC   Population: Caucasian.
CC   Characteristics: Appears to be a progenitor cell line. Produces myoepithelial cells at the stromal-epithelial junction in tumors generated in nude mice.
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg249Gly (c.745A>G); ClinVar=VCV000376654; Zygosity=Unspecified (from parent cell line).
CC   Derived from site: In situ; Breast; UBERON=UBERON_0000310.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_6857 ! HMT-3909S8
SX   Female
AG   61Y
CA   Cancer cell line
DT   Created: 25-02-19; Last updated: 05-10-23; Version: 6
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RX   PubMed=11801722; DOI=10.1242/jcs.115.1.39;
RA   Gudjonsson T., Ronnov-Jessen L., Villadsen R., Rank F., Bissell M.J.,
RA   Petersen O.W.;
RT   "Normal and tumor-derived myoepithelial cells differ in their ability
RT   to interact with luminal breast epithelial cells for polarity and
RT   basement membrane deposition.";
RL   J. Cell Sci. 115:39-50(2002).
//
RX   PubMed=16807805; DOI=10.1007/s10911-005-9586-4;
RA   Gudjonsson T., Adriance M.C., Sternlicht M.D., Petersen O.W.,
RA   Bissell M.J.;
RT   "Myoepithelial cells: their origin and function in breast
RT   morphogenesis and neoplasia.";
RL   J. Mammary Gland Biol. Neoplasia 10:261-272(2005).
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RX   PubMed=22692575; DOI=10.2119/molmed.2012.00091;
RA   Leth-Larsen R., Terp M.G., Christensen A.G., Elias D., Kuhlwein T.,
RA   Jensen O.N., Petersen O.W., Ditzel H.J.;
RT   "Functional heterogeneity within the CD44 high human breast cancer
RT   stem cell-like compartment reveals a gene signature predictive of
RT   distant metastasis.";
RL   Mol. Med. 18:1109-1121(2012).
//