ID   BT147 [Calgary]
AC   CVCL_UK63
SY   BT-147
DR   GEO; GSM1975011
DR   GEO; GSM1975012
DR   GEO; GSM1975013
DR   GEO; GSM1975014
DR   GEO; GSM1975015
DR   GEO; GSM1975016
DR   Wikidata; Q93432835
RX   PubMed=26095605;
RX   PubMed=26245525;
RX   PubMed=27006494;
RX   PubMed=30153289;
CC   Group: Cancer stem cell line.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=26095605).
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Brain; UBERON=UBERON_0000955.
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   55Y
CA   Cancer cell line
DT   Created: 25-02-19; Last updated: 10-04-25; Version: 9
//
RX   PubMed=27006494; DOI=10.1158/1078-0432.CCR-15-1798;
RA   Lun, Xue-Qing
RA   Wells, J. Connor
RA   Grinshtein, Natalie
RA   King, Jennifer C.
RA   Hao, Xiao-Guang
RA   Dang, Ngoc-Ha
RA   Wang, Xiu-Ling
RA   Aman, Ahmed
RA   Uehling, David
RA   Datti, Alessandro
RA   Wrana, Jeffrey L.
RA   Easaw, Jacob Chirakkattu
RA   Luchman, Hema Artee
RA   Weiss, Samuel
RA   Cairncross, J. Gregory
RA   Kaplan, David Ross
RA   Robbins, Stephen M.
RA   Senger, Donna L.
RT   "Disulfiram when combined with copper enhances the therapeutic effects
RT   of temozolomide for the treatment of glioblastoma.";
RL   Clin. Cancer Res. 22:3860-3875(2016).
//
RX   PubMed=30153289; DOI=10.1371/journal.pone.0202860; PMCID=PMC6112648;
RA   Yuan, Alice L.
RA   Ricks, Christian B.
RA   Bohm, Alexandra K.
RA   Lun, Xue-Qing
RA   Maxwell, Lori
RA   Safdar, Shahana
RA   Bukhari, Shazreh
RA   Gerber, Amanda
RA   Sayeed, Wajid
RA   Bering, Elizabeth Ann
RA   Pedersen, Haley
RA   Chan, Jennifer Ai-Wen
RA   Shen, Yao-Qing
RA   Marra, Marco Antonio
RA   Kaplan, David Ross
RA   Mason, Warren P.
RA   Goodman, Lindsey Dale
RA   Ezhilarasan, Ravesanker
RA   Kaufmann, Ascher B.
RA   Cabral, Matthew
RA   Robbins, Stephen M.
RA   Senger, Donna L.
RA   Cahill, Daniel P.
RA   Sulman, Erik P.
RA   Cairncross, J. Gregory
RA   Blough, Michael D.
RT   "ABT-888 restores sensitivity in temozolomide resistant glioma cells
RT   and xenografts.";
RL   PLoS ONE 13:e0202860.1-e0202860.18(2018).
//
RX   PubMed=26245525; DOI=10.1093/neuonc/nov143; PMCID=PMC4767234;
RA   Davis, Brad
RA   Shen, Yao-Qing
RA   Poon, Candice C.
RA   Luchman, Hema Artee
RA   Stechishin, Owen D.M.
RA   Pontifex, Carly Sabine
RA   Wu, Wei
RA   Kelly, John J.P.
RA   Blough, Michael D.
RG   Terry Fox Research Institute Glioblastoma Consortium;
RT   "Comparative genomic and genetic analysis of glioblastoma-derived
RT   brain tumor-initiating cells and their parent tumors.";
RL   Neuro-oncol. 18:350-360(2016).
//
RX   PubMed=26095605; DOI=10.1016/j.stemcr.2015.05.010; PMCID=PMC4618251;
RA   Cusulin, Carlo
RA   Chesnelong, Charles
RA   Bose, Pinaki
RA   Bilenky, Misha
RA   Kopciuk, Karen
RA   Chan, Jennifer Ai-Wen
RA   Cairncross, J. Gregory
RA   Jones, Steven J.M.
RA   Marra, Marco Antonio
RA   Luchman, Hema Artee
RA   Weiss, Samuel
RT   "Precursor states of brain tumor initiating cell lines are predictive
RT   of survival in xenografts and associated with glioblastoma
RT   subtypes.";
RL   Stem Cell Reports 5:1-9(2015).
//