ID   BT025
AC   CVCL_UK41
SY   BT25
DR   GEO; GSM2155020
DR   GEO; GSM2155023
DR   Wikidata; Q93432761
RX   PubMed=19544433;
RX   PubMed=20593219;
RX   PubMed=26095605;
RX   PubMed=27006494;
CC   Group: Cancer stem cell line.
CC   Omics: Transcriptomics; Microarray.
CC   Derived from site: In situ; Brain; UBERON=UBERON_0000955.
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   57Y
CA   Cancer cell line
DT   Created: 25-02-19; Last updated: 10-04-25; Version: 6
//
RX   PubMed=19544433; DOI=10.1002/stem.98;
RA   Kelly, John J.P.
RA   Stechishin, Owen D.M.
RA   Chojnacki, Andrew
RA   Lun, Xue-Qing
RA   Sun, Bei-Chen
RA   Senger, Donna L.
RA   Forsyth, Peter
RA   Auer, Roland N.
RA   Dunn, Jeff F.
RA   Cairncross, J. Gregory
RA   Parney, Ian Frederick
RA   Weiss, Samuel
RT   "Proliferation of human glioblastoma stem cells occurs independently
RT   of exogenous mitogens.";
RL   Stem Cells 27:1722-1733(2009).
//
RX   PubMed=26095605; DOI=10.1016/j.stemcr.2015.05.010; PMCID=PMC4618251;
RA   Cusulin, Carlo
RA   Chesnelong, Charles
RA   Bose, Pinaki
RA   Bilenky, Misha
RA   Kopciuk, Karen
RA   Chan, Jennifer Ai-Wen
RA   Cairncross, J. Gregory
RA   Jones, Steven J.M.
RA   Marra, Marco Antonio
RA   Luchman, Hema Artee
RA   Weiss, Samuel
RT   "Precursor states of brain tumor initiating cell lines are predictive
RT   of survival in xenografts and associated with glioblastoma
RT   subtypes.";
RL   Stem Cell Reports 5:1-9(2015).
//
RX   PubMed=27006494; DOI=10.1158/1078-0432.CCR-15-1798;
RA   Lun, Xue-Qing
RA   Wells, J. Connor
RA   Grinshtein, Natalie
RA   King, Jennifer C.
RA   Hao, Xiao-Guang
RA   Dang, Ngoc-Ha
RA   Wang, Xiu-Ling
RA   Aman, Ahmed
RA   Uehling, David
RA   Datti, Alessandro
RA   Wrana, Jeffrey L.
RA   Easaw, Jacob Chirakkattu
RA   Luchman, Hema Artee
RA   Weiss, Samuel
RA   Cairncross, J. Gregory
RA   Kaplan, David Ross
RA   Robbins, Stephen M.
RA   Senger, Donna L.
RT   "Disulfiram when combined with copper enhances the therapeutic effects
RT   of temozolomide for the treatment of glioblastoma.";
RL   Clin. Cancer Res. 22:3860-3875(2016).
//
RX   PubMed=20593219; DOI=10.1007/s11060-010-0283-9;
RA   Blough, Michael D.
RA   Beauchamp, Desiree C.
RA   Westgate, Morgan R.
RA   Kelly, John J.P.
RA   Cairncross, J. Gregory
RT   "Effect of aberrant p53 function on temozolomide sensitivity of glioma
RT   cell lines and brain tumor initiating cells from glioblastoma.";
RL   J. Neurooncol. 102:1-7(2011).
//