ID   HuWa-TERT
AC   CVCL_UJ99
SY   HuWaTERT1; HuWaTERT
DR   Wikidata; Q94309834
RX   DOI=10.25904/1912/492;
RX   PubMed=30627956;
RX   PubMed=35540658;
CC   Group: Endangered species/breed cell line.
CC   Group: Cetacean cell line.
CC   Doubling time: 25 hours (PubMed=30627956).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
OX   NCBI_TaxID=9773; ! Megaptera novaeangliae (Humpback whale)
HI   CVCL_4U66 ! HuWa1
SX   Male
AG   1-2Y
CA   Telomerase immortalized cell line
DT   Created: 25-02-19; Last updated: 19-12-24; Version: 10
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RX   DOI=10.25904/1912/492;
RA   Burkard M.;
RT   "Humpback whale cell lines as an in vitro tool for toxicity assessment.";
RL   Thesis PhD (2017); Griffith University; Brisbane; Australia.
//
RX   PubMed=30627956; DOI=10.1007/s10565-018-09457-1; PMCID=PMC6757015;
RA   Burkard M., Bengtson Nash S.M., Gambaro G., Whitworth D.J., Schirmer K.;
RT   "Lifetime extension of humpback whale skin fibroblasts and their
RT   response to lipopolysaccharide (LPS) and a mixture of polychlorinated
RT   biphenyls (Aroclor).";
RL   Cell Biol. Toxicol. 35:387-398(2019).
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RX   PubMed=35540658; DOI=10.1039/c9ra05352b; PMCID=PMC9076109;
RA   Maner J., Burkard M., Cassano J.C., Bengtson Nash S.M., Schirmer K.,
RA   Suter M.J.-F.;
RT   "Hexachlorobenzene exerts genotoxic effects in a humpback whale cell
RT   line under stable exposure conditions.";
RL   RSC Adv. 9:39447-39457(2019).
//