ID   POT1a F/F POT1b F/F (#20431-5)
AC   CVCL_UJ01
SY   POT1a F/F POT1b F/F(#20431-5)
DR   ATCC; CRL-3323
DR   Wikidata; Q98128656
RX   PubMed=16839877;
CC   Characteristics: Embryonic fibroblasts that have loxP sites on both sides of the 3rd coding exon of mouse Pot1a and Pot1b genes. Pot1a anb Pot1b knockout can be effected by transduction of Cre recombinase into the cell line (ATCC=CRL-3323).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
CC   Breed/subspecies: 129P2/Ola x C57BL/6J.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   13-14FD
CA   Transformed cell line
DT   Created: 25-02-19; Last updated: 19-12-24; Version: 6
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RX   PubMed=16839877; DOI=10.1016/j.cell.2006.04.044;
RA   Hockemeyer D., Daniels J.-P., Takai H., de Lange T.;
RT   "Recent expansion of the telomeric complex in rodents: two distinct
RT   POT1 proteins protect mouse telomeres.";
RL   Cell 126:63-77(2006).
//