ID   HEK293 CYP2D6*10
AC   CVCL_UH09
SY   CYP2D6*10 (P34S/S486T) Expressing HEK293 Cell Line
DR   Wikidata; Q94093000
RX   PubMed=28603633;
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:2625; CYP2D6 (Note=With p.Pro34Ser and p.Ser486Thr).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Miscellaneous: Cell line has been lost. Attempt to re-clone it are underway.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0045 ! HEK293
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 13-11-18; Last updated: 19-12-24; Version: 8
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RX   PubMed=28603633; DOI=10.1002/prp2.314; PMCID=PMC5464343;
RA   Peterson A., Xia Z.-P., Chen G., Lazarus P.;
RT   "In vitro metabolism of exemestane by hepatic cytochrome P450s: impact
RT   of nonsynonymous polymorphisms on formation of the active metabolite
RT   17beta-dihydroexemestane.";
RL   Pharmacol. Res. Perspect. 5:e00314.1-e00314.16(2017).
//