ID   HEK293 CYP2C8*4-V5
AC   CVCL_UG93
SY   CYP2C8*4 (I264M - V5 tag) Expressing HEK293 Cell Line
DR   Kerafast; EWU016
DR   Wikidata; Q94092969
RX   PubMed=28603633;
CC   Characteristics: Expresses CYP2C8*4 with a C-terminal V5 tag.
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:2622; CYP2C8 (Note=With p.Ile264Met).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5.
CC   Discontinued: Kerafast; EWU016; true.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0045 ! HEK293
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 13-11-18; Last updated: 14-08-25; Version: 8
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RX   PubMed=28603633; DOI=10.1002/prp2.314; PMCID=PMC5464343;
RA   Peterson, Amity
RA   Xia, Zu-Ping
RA   Chen, Gang
RA   Lazarus, Philip
RT   "In vitro metabolism of exemestane by hepatic cytochrome P450s: impact
RT   of nonsynonymous polymorphisms on formation of the active metabolite
RT   17beta-dihydroexemestane.";
RL   Pharmacol. Res. Perspect. 5:e00314.1-e00314.16(2017).
//