ID   TRF1 F/F
AC   CVCL_UE12
DR   ATCC; CRL-3316
DR   Wikidata; Q98133536
RX   PubMed=19596237;
CC   Characteristics: Embryonic fibroblasts that have loxP sites on both sides of the 1st coding exon of mouse Terf1 gene. Terf1 knockout can be effected by transduction of Cre recombinase into the cell line (ATCC=CRL-3316).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
CC   Breed/subspecies: 129P2/Ola x C57BL/6J.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   13-14FD
CA   Transformed cell line
DT   Created: 13-11-18; Last updated: 14-08-25; Version: 7
//
RX   PubMed=19596237; DOI=10.1016/j.cell.2009.06.021; PMCID=PMC2723738;
RA   Sfeir, Agnel
RA   Kosiyatrakul, Settapong T.
RA   Hockemeyer, Dirk
RA   MacRae, Sheila L.
RA   Karlseder, Jan
RA   Schildkraut, Carl L.
RA   de Lange, Titia
RT   "Mammalian telomeres resemble fragile sites and require TRF1 for
RT   efficient replication.";
RL   Cell 138:90-103(2009).
//