ID   MeWo-LC1
AC   CVCL_U937
DR   cancercelllines; CVCL_U937
DR   Wikidata; Q54905347
RX   PubMed=3000950;
CC   Group: Serum/protein free medium cell line.
CC   Population: Caucasian.
CC   Doubling time: 42 +- 2 hours (PubMed=3000950).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.237_238CC>TT) (c.237_238delinsTT) (p.Pro94Leu, c.280_281CC>TT); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6877; MAPK3; Simple; p.Pro246Ser (c.736C>T); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln317Ter (c.949C>T); ClinVar=VCV000450344; Zygosity=Unspecified (from parent cell line).
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
DI   NCIt; C3510; Cutaneous melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0445 ! MeWo
SX   Male
AG   78Y
CA   Cancer cell line
DT   Created: 16-04-14; Last updated: 19-12-24; Version: 17
//
RX   PubMed=3000950; DOI=10.1002/ijc.2910370120;
RA   Sauvaigo, Sylvie
RA   Fretts, Ruth E.
RA   Riopelle, Richard John
RA   Lagarde, Alain E.
RT   "Autonomous proliferation of MeWo human melanoma cell lines in
RT   serum-free medium: secretion of growth-stimulating activities.";
RL   Int. J. Cancer 37:123-132(1986).
//