ID   Neo Jurkat
AC   CVCL_U621
DR   ATCC; CRL-2898
DR   cancercelllines; CVCL_U621
DR   Wikidata; Q54930401
RX   PubMed=10567572;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:959; BAX; Simple; p.Glu41Argfs*19 (c.121delG); ClinVar=VCV000009512; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:959; BAX; Simple; p.Glu41Glyfs*33 (c.121dupG); ClinVar=VCV000009511; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Arg505Cys (c.1513C>T); ClinVar=VCV000069961; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6079; INPP5D; Simple; p.Gln345Ter (c.1033C>T); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6079; INPP5D; Simple; c.1097+1065_1097+1112del47; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7325; MSH2; Simple; p.Arg711Ter (c.2131C>T); ClinVar=VCV000090903; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7329; MSH6; Simple; p.Phe1088Serfs*2 (c.3261delC); ClinVar=VCV000089363; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: T-cell; CL=CL_0000084.
ST   Source(s): ATCC=CRL-2898
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 8,12
ST   D16S539: 11
ST   D18S51: 13,21
ST   D19S433: 14,15.2
ST   D21S11: 31.2,33.2
ST   D2S1338: 19,23
ST   D3S1358: 15,17
ST   D5S818: 9
ST   D7S820: 8,12
ST   D8S1179: 13,14
ST   FGA: 20,21
ST   Penta D: 11,13
ST   Penta E: 10,12
ST   TH01: 6,9.3
ST   TPOX: 8,10
ST   vWA: 18
DI   NCIt; C7953; Childhood T acute lymphoblastic leukemia
DI   ORDO; Orphanet_99861; Precursor T-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0065 ! Jurkat
SX   Male
AG   14Y
CA   Cancer cell line
DT   Created: 16-04-14; Last updated: 19-12-24; Version: 20
//
RX   PubMed=10567572; DOI=10.1128/mcb.19.12.8469; PMCID=PMC84954;
RA   Yamamoto K., Ichijo H., Korsmeyer S.J.;
RT   "BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal
RT   protein kinase pathway normally activated at G(2)/M.";
RL   Mol. Cell. Biol. 19:8469-8478(1999).
//