ID   TTE3
AC   CVCL_U448
AS   CVCL_9808
SY   TTE 3
DR   EFO; EFO_0002868
DR   Wikidata; Q54973226
RX   PubMed=11832784;
RX   PubMed=15541572;
RX   PubMed=17233813;
RX   PubMed=17543550;
CC   Characteristics: Proliferates at the permissive temperature (33 Celsius). Growth is signicantly prevented at the nonpermissive temperature (39 Celsius) (PubMed=11832784).
CC   Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
CC   Omics: Transcriptomics; Microarray.
CC   Misspelling: TT3E; EFO=EFO_0002868.
CC   Derived from site: In situ; Testis; UBERON=UBERON_0000473.
CC   Cell type: Sertoli cell; CL=CL_0000216.
CC   Breed/subspecies: C57BL/6 SV40-tsA58 transgenic.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Male
AG   2M
CA   Conditionally immortalized cell line
DT   Created: 03-02-14; Last updated: 10-04-25; Version: 16
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RX   PubMed=11832784; DOI=10.1016/S0022-5347(05)65359-1;
RA   Tabuchi Y., Ohta S., Yanai N., Obinata M., Kondo T., Fuse H.,
RA   Asano S.;
RT   "Development of the conditionally immortalized testicular Sertoli cell
RT   line TTE3 expressing Sertoli cell specific genes from mice transgenic
RT   for temperature sensitive simian virus 40 large T antigen gene.";
RL   J. Urol. 167:1538-1545(2002).
//
RX   PubMed=15541572; DOI=10.1016/j.mce.2003.05.001;
RA   Rahman N.A., Huhtaniemi I.T.;
RT   "Testicular cell lines.";
RL   Mol. Cell. Endocrinol. 228:53-65(2004).
//
RX   PubMed=17233813; DOI=10.1111/j.1349-7006.2007.00399.x; PMCID=PMC11159456;
RA   Obinata M.;
RT   "The immortalized cell lines with differentiation potentials: their
RT   establishment and possible application.";
RL   Cancer Sci. 98:275-283(2007).
//
RX   PubMed=17543550; DOI=10.1016/j.cellbi.2007.04.007;
RA   Tabuchi Y., Takasaki I., Suto A., Kondo T., Suzuki Y., Obinata M.;
RT   "Genetic networks in nonpermissive temperature-induced cell
RT   differentiation of Sertoli TTE3 cells harboring temperature-sensitive
RT   SV40 large T-antigen.";
RL   Cell Biol. Int. 31:1231-1236(2007).
//