ID   B76.1/Huh7
AC   CVCL_U443
SY   B76.1/Huh-7; B76.1
DR   cancercelllines; CVCL_U443
DR   Wikidata; Q54752833
RX   PubMed=12097587;
CC   Population: Japanese.
CC   Sequence variation: Mutation; HGNC; HGNC:6307; KDR; Simple; p.Gln472His (c.1416A>T); ClinVar=VCV000134603; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:20932; POLD3; Simple; p.Lys109Arg (c.326A>G) (p.Lys70Arg, c.209A>G); Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
DI   NCIt; C7956; Adult hepatocellular carcinoma
DI   ORDO; Orphanet_210159; Adult hepatocellular carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_U442 ! B76/Huh7
SX   Male
AG   57Y
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 19-12-24; Version: 16
//
RX   PubMed=12097587; DOI=10.1128/JVI.76.15.7736-7746.2002; PMCID=PMC136363;
RA   De Tomassi, Amedeo
RA   Pizzuti, Maura
RA   Graziani, Rita
RA   Sbardellati, Andrea
RA   Altamura, Sergio
RA   Paonessa, Giacomo
RA   Traboni, Cinzia
RT   "Cell clones selected from the Huh7 human hepatoma cell line support
RT   efficient replication of a subgenomic GB virus B replicon.";
RL   J. Virol. 76:7736-7746(2002).
//