ID   MR6
AC   CVCL_U183
DR   CLO; CLO_0050916
DR   BioSample; SAMN03470988
DR   BioSample; SAMN03472275
DR   RCB; RCB0505
DR   Wikidata; Q54906577
RX   PubMed=2372878;
RX   PubMed=3608093;
RX   PubMed=25877200;
CC   Population: African American.
CC   Selected for resistance to: ChEBI; CHEBI:21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): PubMed=25877200; RCB
ST   Amelogenin: X
ST   CSF1PO: 9,10
ST   D13S317: 13.3
ST   D16S539: 9,10
ST   D18S51: 16
ST   D19S433: 13,14
ST   D21S11: 27,28
ST   D2S1338: 17
ST   D3S1358: 15,18
ST   D5S818: 11,12
ST   D7S820: 8
ST   D8S1179: 12
ST   FGA: 21
ST   Penta D: 8
ST   Penta E: 7,16,17
ST   TH01: 7 (PubMed=25877200)
ST   TH01: 7,9.3 (RCB)
ST   TPOX: 8,12
ST   vWA: 15,16,18 (RCB)
ST   vWA: 15,18 (PubMed=25877200)
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_U209 ! HeLa S3 mer-
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 05-10-23; Version: 14
//
RX   PubMed=2372878; DOI=10.1093/carcin/11.7.1209;
RA   Ishida R., Utsumi K.R.;
RT   "Differences in induction of sister chromatid exchanges in MNNG-resistant
RT   HeLa S3 Mer- cell lines.";
RL   Carcinogenesis 11:1209-1212(1990).
//
RX   PubMed=3608093; DOI=10.1093/carcin/8.8.1109;
RA   Ishida R., Takahashi T.;
RT   "N-methyl-N'-nitro-N-nitrosoguanidine-resistant HeLa S3 cells still
RT   have little O6-methylguanine-DNA methyltransferase activity and are
RT   hypermutable by alkylating agents.";
RL   Carcinogenesis 8:1109-1113(1987).
//
RX   PubMed=25877200; DOI=10.1038/nature14397;
RA   Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M.,
RA   Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S.,
RA   Neve R.M.;
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).
//