ID   MR6
AC   CVCL_U183
DR   CLO; CLO_0050916
DR   BioSample; SAMN03470988
DR   BioSample; SAMN03472275
DR   RCB; RCB0505
DR   Wikidata; Q54906577
RX   PubMed=2372878;
RX   PubMed=3608093;
RX   PubMed=25877200;
CC   Population: African American.
CC   Selected for resistance to: ChEBI; CHEBI_21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): PubMed=25877200; RCB=RCB0505
ST   Amelogenin: X
ST   CSF1PO: 9,10
ST   D13S317: 13.3
ST   D16S539: 9,10
ST   D18S51: 16
ST   D19S433: 13,14
ST   D21S11: 27,28
ST   D2S1338: 17
ST   D3S1358: 15,18
ST   D5S818: 11,12
ST   D7S820: 8
ST   D8S1179: 12
ST   FGA: 21
ST   Penta D: 8
ST   Penta E: 7,16,17
ST   TH01: 7 (PubMed=25877200)
ST   TH01: 7,9.3 (RCB=RCB0505)
ST   TPOX: 8,12
ST   vWA: 15,16,18 (RCB=RCB0505)
ST   vWA: 15,18 (PubMed=25877200)
DI   NCIt; C27677; Human papillomavirus-related endocervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_U209 ! HeLa S3 mer-
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 10-04-25; Version: 17
//
RX   PubMed=3608093; DOI=10.1093/carcin/8.8.1109;
RA   Ishida, Ryoji
RA   Takahashi, Taijo
RT   "N-methyl-N'-nitro-N-nitrosoguanidine-resistant HeLa S3 cells still
RT   have little O6-methylguanine-DNA methyltransferase activity and are
RT   hypermutable by alkylating agents.";
RL   Carcinogenesis 8:1109-1113(1987).
//
RX   PubMed=2372878; DOI=10.1093/carcin/11.7.1209;
RA   Ishida, Ryoji
RA   Utsumi, Kazuhiko R.
RT   "Differences in induction of sister chromatid exchanges in MNNG-resistant
RT   HeLa S3 Mer- cell lines.";
RL   Carcinogenesis 11:1209-1212(1990).
//
RX   PubMed=25877200; DOI=10.1038/nature14397;
RA   Yu, Ma-Mie
RA   Selvaraj, Suresh K.
RA   Liang-Chu, May M.Y.
RA   Aghajani, Sahar
RA   Busse, Matthew
RA   Yuan, Jean
RA   Lee, Genee
RA   Peale, Franklin V.
RA   Klijn, Christiaan
RA   Bourgon, Richard
RA   Kaminker, Joshua S.
RA   Neve, Richard M.
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).
//