ID   A2780-M
AC   CVCL_TZ68
DR   cancercelllines; CVCL_TZ68
DR   Wikidata; Q93311561
RX   PubMed=30046596;
CC   Population: African American.
CC   Characteristics: Compared to the parent cell line, has high invasiveness and motility.
CC   Sequence variation: Mutation; HGNC; HGNC:795; ATM; Simple; p.Pro604Ser (c.1810C>T); ClinVar=VCV000127343; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu365Lys (c.1093G>A); ClinVar=VCV000419222; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys128_Arg130del (c.383_391del9); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:17271; RRAS2; Simple; p.Gln72Leu (c.215A>T); ClinVar=VCV000009447; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
ST   Source(s): PubMed=30046596
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D12S391: 18,19,20
ST   D13S317: 12,13
ST   D16S539: 11,13
ST   D18S51: 16,18,19
ST   D19S433: 12
ST   D21S11: 28
ST   D2S1338: 21,22
ST   D3S1358: 14,16
ST   D5S818: 11,12
ST   D6S1043: 11,19
ST   D7S820: 10
ST   D8S1179: 15,17
ST   FGA: 19,24
ST   Penta D: 9,10
ST   Penta E: 10,13
ST   TH01: 6
ST   TPOX: 8,10
ST   vWA: 15,16
DI   NCIt; C7979; Ovarian endometrioid adenocarcinoma
DI   ORDO; Orphanet_454723; Endometrioid carcinoma of ovary
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0134 ! A2780
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 13-11-18; Last updated: 10-04-25; Version: 12
//
RX   PubMed=30046596; DOI=10.1155/2018/3972534; PMCID=PMC6036838;
RA   Jiang, Rui-Bin
RA   Cheng, Guo-Ping
RA   Zheng, Zhi-Guo
RA   Ni, Mao-Wei
RA   Wan, Dan-Ying
RA   Feng, Jian-Guo
RA   Gu, Lin-Hui
RT   "Establishment and characterization of a highly metastatic ovarian
RT   cancer cell line.";
RL   BioMed Res. Int. 2018:3972534.1-3972534.9(2018).
//