ID   HAP1 TIA1 (-) 2
AC   CVCL_TS30
SY   HZGHC003048c010; TIA1 knockout cell line 5bp deletion
DR   cancercelllines; CVCL_TS30
DR   Horizon_Discovery; HZGHC003048c010
DR   Wikidata; Q54880483
RX   DOI=10.12688/f1000research.133645.1;
CC   Group: Haploid karyotype cell line.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; 11802; TIA1.
CC   Sequence variation: Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Ser215Gly (c.643A>G); ClinVar=VCV000265337; Zygosity=Hemizygous (from parent cell line).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C3174; Chronic myelogenous leukemia, BCR-ABL1 positive
DI   ORDO; Orphanet_521; Chronic myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_Y019 ! HAP1
SX   Male
AG   40Y
CA   Cancer cell line
DT   Created: 14-05-18; Last updated: 05-10-23; Version: 9
//
RX   DOI=10.12688/f1000research.133645.1;
RA   Fotouhi M., Worrall D., Ayoubi R., Southern K., McPherson P.S.,
RA   Laflamme C.;
RT   "The identification of high-performing antibodies for RNA-binding
RT   protein TIA1 for use in western blot, immunoprecipitation and
RT   immunofluorescence.";
RL   F1000Research 12:745.1-745.11(2023).
//