ID   K21S4
AC   CVCL_T836
SY   K21-S04; HPS0073
DR   GEO; GSM1227438
DR   GEO; GSM1227439
DR   RCB; HPS0073
DR   SKIP; SKIP000140
DR   Wikidata; Q54899272
RX   Patent=US10519422;
RX   PubMed=21347327;
RX   PubMed=24527394;
CC   Sequence variation: Mutation; HGNC; HGNC:10263; RP1; Simple; p.Leu721Profs*2 (c.2161dupC) (c.2161_2162insC); Zygosity=Unspecified (PubMed=21347327).
CC   Omics: Transcriptomics; Microarray.
CC   Discontinued: SKIP; SKIP000140; probable.
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
DI   NCIt; C85045; Retinitis pigmentosa
DI   ORDO; Orphanet_791; Retinitis pigmentosa
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   67Y
CA   Induced pluripotent stem cell
DT   Created: 03-02-14; Last updated: 10-04-25; Version: 17
//
RX   PubMed=21347327; DOI=10.1371/journal.pone.0017084; PMCID=PMC3037398;
RA   Jin, Zi-Bing
RA   Okamoto, Satoshi
RA   Osakada, Fumitaka
RA   Homma, Kohei
RA   Assawachananont, Juthaporn
RA   Hirami, Yasuhiko
RA   Iwata, Takeshi
RA   Takahashi, Masayo
RT   "Modeling retinal degeneration using patient-specific induced
RT   pluripotent stem cells.";
RL   PLoS ONE 6:e17084.1-e17084.8(2011).
//
RX   Patent=US10519422;
RA   Takahashi, Masayo
RA   Okamoto, Satoshi
RA   Sakai, Noriko
RT   "Method of producing human retinal pigment epithelial cells.";
RL   Patent number US10519422, 31-Dec-2019.
//
RX   PubMed=24527394; DOI=10.1016/j.stemcr.2013.12.007; PMCID=PMC3923225;
RA   Kamao, Hiroyuki
RA   Mandai, Michiko
RA   Okamoto, Satoshi
RA   Sakai, Noriko
RA   Suga, Akiko
RA   Sugita, Sunao
RA   Kiryu, Junichi
RA   Takahashi, Masayo
RT   "Characterization of human induced pluripotent stem cell-derived
RT   retinal pigment epithelium cell sheets aiming for clinical
RT   application.";
RL   Stem Cell Reports 2:205-218(2014).
//