ID   K21S4
AC   CVCL_T836
SY   K21-S04; HPS0073
DR   GEO; GSM1227438
DR   GEO; GSM1227439
DR   RCB; HPS0073
DR   SKIP; SKIP000140
DR   Wikidata; Q54899272
RX   Patent=US10519422;
RX   PubMed=21347327;
RX   PubMed=24527394;
CC   Sequence variation: Mutation; HGNC; 10263; RP1; Simple; p.Leu721Profs*2 (c.2161dupC) (c.2161_2162insC); Zygosity=Unspecified (PubMed=21347327).
CC   Omics: Transcriptome analysis by microarray.
CC   Discontinued: SKIP; SKIP000140; probable.
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
DI   NCIt; C85045; Retinitis pigmentosa
DI   ORDO; Orphanet_791; Retinitis pigmentosa
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   67Y
CA   Induced pluripotent stem cell
DT   Created: 03-02-14; Last updated: 29-06-23; Version: 15
//
RX   Patent=US10519422;
RA   Takahashi M., Okamoto S., Sakai N.;
RT   "Method of producing human retinal pigment epithelial cells.";
RL   Patent number US10519422, 31-Dec-2019.
//
RX   PubMed=21347327; DOI=10.1371/journal.pone.0017084;
RA   Jin Z.-B., Okamoto S., Osakada F., Homma K., Assawachananont J.,
RA   Hirami Y., Iwata T., Takahashi M.;
RT   "Modeling retinal degeneration using patient-specific induced
RT   pluripotent stem cells.";
RL   PLoS ONE 6:E17084-E17084(2011).
//
RX   PubMed=24527394; DOI=10.1016/j.stemcr.2013.12.007;
RA   Kamao H., Mandai M., Okamoto S., Sakai N., Suga A., Sugita S.,
RA   Kiryu J., Takahashi M.;
RT   "Characterization of human induced pluripotent stem cell-derived
RT   retinal pigment epithelium cell sheets aiming for clinical
RT   application.";
RL   Stem Cell Reports 2:205-218(2014).
//