ID   K11PD17
AC   CVCL_T834
SY   K11-P17; HPS0072
DR   GEO; GSM1227437
DR   RCB; HPS0072
DR   SKIP; SKIP000138
DR   Wikidata; Q54899248
RX   Patent=US10519422;
RX   PubMed=21347327;
RX   PubMed=24527394;
CC   Sequence variation: Mutation; HGNC; HGNC:10288; RP9; Simple; p.His137Leu (c.410A>T); ClinVar=VCV000003334; Zygosity=Unspecified (PubMed=21347327).
CC   Omics: Transcriptomics; Microarray.
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
DI   NCIt; C85045; Retinitis pigmentosa
DI   ORDO; Orphanet_791; Retinitis pigmentosa
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_T833 ! K11M4
OI   CVCL_T835 ! K11PD18
SX   Female
AG   42Y
CA   Induced pluripotent stem cell
DT   Created: 03-02-14; Last updated: 10-04-25; Version: 18
//
RX   Patent=US10519422;
RA   Takahashi M., Okamoto S., Sakai N.;
RT   "Method of producing human retinal pigment epithelial cells.";
RL   Patent number US10519422, 31-Dec-2019.
//
RX   PubMed=21347327; DOI=10.1371/journal.pone.0017084; PMCID=PMC3037398;
RA   Jin Z.-B., Okamoto S., Osakada F., Homma K., Assawachananont J.,
RA   Hirami Y., Iwata T., Takahashi M.;
RT   "Modeling retinal degeneration using patient-specific induced
RT   pluripotent stem cells.";
RL   PLoS ONE 6:e17084.1-e17084.8(2011).
//
RX   PubMed=24527394; DOI=10.1016/j.stemcr.2013.12.007; PMCID=PMC3923225;
RA   Kamao H., Mandai M., Okamoto S., Sakai N., Suga A., Sugita S.,
RA   Kiryu J., Takahashi M.;
RT   "Characterization of human induced pluripotent stem cell-derived
RT   retinal pigment epithelium cell sheets aiming for clinical
RT   application.";
RL   Stem Cell Reports 2:205-218(2014).
//