ID   UPS-1
AC   CVCL_T762
DR   RCB; RCB4451
DR   Wikidata; Q54991719
RX   PubMed=7876305;
RX   PubMed=26420878;
CC   Characteristics: Defective in the uptake of fluorescent phosphatidylserine analogs by the nonendocytic pathway (PubMed=7876305).
CC   Sequence variation: Mutation; UniProtKB; A0A061HXB8; Atp11c; Simple; p.Trp836Ter (c.2508G>A) (W664X); Zygosity=Homozygous (PubMed=26420878).
CC   Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_0214 ! CHO-K1
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 03-02-14; Last updated: 19-12-24; Version: 10
//
RX   PubMed=26420878; DOI=10.1194/jlr.M062547; PMCID=PMC4617402;
RA   Takada, Naoto
RA   Takatsu, Hiroyuki
RA   Miyano, Rie
RA   Nakayama, Kazuhisa
RA   Shin, Hye-Won
RT   "ATP11C mutation is responsible for the defect in phosphatidylserine
RT   uptake in UPS-1 cells.";
RL   J. Lipid Res. 56:2151-2157(2015).
//
RX   PubMed=7876305; DOI=10.1083/jcb.128.5.793; PMCID=PMC2120400;
RA   Hanada, Kentaro
RA   Pagano, Richard Emil
RT   "A Chinese hamster ovary cell mutant defective in the non-endocytic
RT   uptake of fluorescent analogs of phosphatidylserine: isolation using a
RT   cytosol acidification protocol.";
RL   J. Cell Biol. 128:793-804(1995).
//