ID   HAP1 GABARAP (-) 3
AC   CVCL_SP34
SY   HZGHC003054c004; GABARAP knockout cell line 1bp deletion in exon 3
DR   cancercelllines; CVCL_SP34
DR   Horizon_Discovery; HZGHC003054c004
DR   Wikidata; Q54874128
RX   PubMed=30679523;
CC   Group: Haploid karyotype cell line.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; 4067; GABARAP.
CC   Sequence variation: Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 13 fused to ABL1 exon 2 (b2a2 transcript) (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Ser215Gly (c.643A>G); ClinVar=VCV000265337; Zygosity=Hemizygous (from parent cell line).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C3174; Chronic myelogenous leukemia, BCR-ABL1 positive
DI   ORDO; Orphanet_521; Chronic myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_Y019 ! HAP1
SX   Male
AG   40Y
CA   Cancer cell line
DT   Created: 14-05-18; Last updated: 02-05-24; Version: 11
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RX   PubMed=30679523; DOI=10.1038/s41598-018-36717-1;
RA   Simons I.M., Mohrluder J., Feederle R., Kremmer E., Zobel T.,
RA   Dobner J., Bleffert N., Hoffmann S., Willbold D.;
RT   "The highly GABARAP specific rat monoclonal antibody 8H5 visualizes
RT   GABARAP in immunofluorescence imaging at endogenous levels.";
RL   Sci. Rep. 9:526-526(2019).
//