ID   HAP1 APP (-) 1
AC   CVCL_SD04
SY   HZGHC005368c010; APP knockout cell line 2bp deletion; HAP1 APP (-)
DR   cancercelllines; CVCL_SD04
DR   Horizon_Discovery; HZGHC005368c010
DR   Wikidata; Q54872691
RX   DOI=10.12688/f1000research.139867.1;
CC   Group: Haploid karyotype cell line.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; 620; APP.
CC   Sequence variation: Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Ser215Gly (c.643A>G); ClinVar=VCV000265337; Zygosity=Hemizygous (from parent cell line).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C3174; Chronic myelogenous leukemia, BCR-ABL1 positive
DI   ORDO; Orphanet_521; Chronic myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_Y019 ! HAP1
SX   Male
AG   40Y
CA   Cancer cell line
DT   Created: 14-05-18; Last updated: 05-10-23; Version: 10
//
RX   DOI=10.12688/f1000research.139867.1;
RA   Ayoubi R., Fotouhi M., Worrall D., Southern K., Laflamme C.;
RT   "Identification of high-performing antibodies for amyloid-beta
RT   precursor protein for use in western blot, immunoprecipitation and
RT   immunofluorescence.";
RL   F1000Research 12:956.1-956.10(2023).
//