ID   BIN-67
AC   CVCL_S987
SY   Bin-67; BIN67
DR   BTO; BTO:0005818
DR   ArrayExpress; E-MEXP-3872
DR   ArrayExpress; E-MTAB-1584
DR   cancercelllines; CVCL_S987
DR   Cell_Model_Passport; SIDM01516
DR   Cosmic; 1948264
DR   Cosmic; 2141841
DR   Cosmic; 2161693
DR   DepMap; ACH-001278
DR   GEO; GSM1622407
DR   Wikidata; Q54796702
RX   PubMed=1331173;
RX   PubMed=2845729;
RX   PubMed=23433318;
RX   PubMed=24658002;
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Sequence variation: Mutation; HGNC; 11100; SMARCA4; Simple; c.2438+1G>A; ClinVar=VCV000537781; Zygosity=Heterozygous; Note=Splice donor mutation (PubMed=24658002; DepMap=ACH-001278).
CC   Sequence variation: Mutation; HGNC; 11100; SMARCA4; Simple; c.2439-2A>T; Zygosity=Heterozygous; Note=Splice acceptor mutation (PubMed=24658002; DepMap=ACH-001278).
CC   Omics: Deep exome analysis.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Miscellaneous: STR profile from personal communication of Garson, Kenneth.
CC   Derived from site: Metastatic; Pelvis; UBERON=UBERON_0002355.
ST   Source(s): Direct_author_submission
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 10,12
ST   D16S539: 12
ST   D18S51: 13,19
ST   D19S433: 14,15.2
ST   D21S11: 30
ST   D2S1338: 17,25
ST   D3S1358: 15,19
ST   D5S818: 11,12
ST   D7S820: 9
ST   D8S1179: 14
ST   FGA: 22,23
ST   TH01: 6,9.3
ST   TPOX: 11
ST   vWA: 14,18
DI   NCIt; C40439; Ovarian small cell carcinoma, hypercalcemic type
DI   ORDO; Orphanet_370396; Small cell carcinoma of the ovary
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 10-09-24; Version: 20
//
RX   PubMed=1331173; DOI=10.1172/JCI116046; PMCID=PMC443230;
RA   Gorn A.H., Lin H.Y., Yamin M., Auron P.E., Flannery M.R., Tapp D.R.,
RA   Manning C.A., Lodish H.F., Krane S.M., Goldring S.R.;
RT   "Cloning, characterization, and expression of a human calcitonin
RT   receptor from an ovarian carcinoma cell line.";
RL   J. Clin. Invest. 90:1726-1735(1992).
//
RX   PubMed=2845729; DOI=10.1002/jbmr.5650010309;
RA   Upchurch K.S., Parker L.M., Scully R.E., Krane S.M.;
RT   "Differential cyclic AMP responses to calcitonin among human ovarian
RT   carcinoma cell lines: a calcitonin-responsive line derived from a rare
RT   tumor type.";
RL   J. Bone Miner. Res. 1:299-304(1986).
//
RX   PubMed=23433318; DOI=10.1186/1750-1172-8-33; PMCID=PMC3635907;
RA   Gamwell L.F., Gambaro K., Merziotis M., Crane C., Arcand S.L.,
RA   Bourada V., Davis C., Squire J.A., Huntsman D.G., Tonin P.N.,
RA   Vanderhyden B.C.;
RT   "Small cell ovarian carcinoma: genomic stability and responsiveness to
RT   therapeutics.";
RL   Orphanet J. Rare Dis. 8:33.1-33.14(2013).
//
RX   PubMed=24658002; DOI=10.1038/ng.2931;
RA   Witkowski L., Carrot-Zhang J., Albrecht S., Fahiminiya S., Hamel N.,
RA   Tomiak E., Grynspan D., Saloustros E., Nadaf J., Rivera B., Gilpin C.,
RA   Castellsague E., Silva-Smith R., Plourde F., Wu M., Saskin A.,
RA   Arseneault M., Karabakhtsian R.G., Reilly E.A., Ueland F.R.,
RA   Margiolaki A., Pavlakis K., Castellino S.M., Lamovec J., Mackay H.J.,
RA   Roth L.M., Ulbright T.M., Bender T.A., Georgoulias V., Longy M.,
RA   Berchuck A., Tischkowitz M., Nagel I., Siebert R., Stewart C.J.R.,
RA   Arseneau J., McCluggage W.G., Clarke B.A., Riazalhosseini Y.,
RA   Hasselblatt M., Majewski J., Foulkes W.D.;
RT   "Germline and somatic SMARCA4 mutations characterize small cell
RT   carcinoma of the ovary, hypercalcemic type.";
RL   Nat. Genet. 46:438-443(2014).
//