ID   HPDE-6/E6E7
AC   CVCL_S972
SY   HPDE6/E6E7; HPDE6-E6E7; HPDE6E6E7; Human Pancreatic Duct Epithelial-6 E6E7 immortalized
DR   EFO; EFO_0005711
DR   ENCODE; ENCBS224AAA
DR   GEO; GSM621854
DR   GEO; GSM816639
DR   Wikidata; Q54890283
RX   PubMed=8669463;
RX   PubMed=11073822;
WW   Info; ENCODE; -; http://genome.ucsc.edu/ENCODE/protocols/cell/human/HPDE6-E6E7_Crawford_protocol.pdf
CC   Part of: ENCODE project common cell types; tier 3.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Donor information: Established from a patient suffering from a cystadenocarcinoma in the tail of her pancreas.
CC   Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
CC   Cell type: Pancreatic ductal cell; CL=CL_0002079.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_4376 ! HPDE
SX   Female
AG   63Y
CA   Transformed cell line
DT   Created: 03-02-14; Last updated: 14-08-25; Version: 20
CH   CVCL_0P37 ! HPDE6c11
CH   CVCL_0P38 ! HPDE6c7
//
RX   PubMed=8669463; PMCID=PMC1861644;
RA   Furukawa, Toru
RA   Duguid, William Paris
RA   Rosenberg, Lawrence
RA   Viallet, Jean
RA   Galloway, Denise A.
RA   Tsao, Ming-Sound
RT   "Long-term culture and immortalization of epithelial cells from normal
RT   adult human pancreatic ducts transfected by the E6E7 gene of human
RT   papilloma virus 16.";
RL   Am. J. Pathol. 148:1763-1770(1996).
//
RX   PubMed=11073822; DOI=10.1016/S0002-9440(10)64800-6; PMCID=PMC1885733;
RA   Ouyang, Hong
RA   Mou, Lun-Jun
RA   Luk, Catherine
RA   Liu, Ni
RA   Karaskova, Jana
RA   Squire, Jeremy Andrew
RA   Tsao, Ming-Sound
RT   "Immortal human pancreatic duct epithelial cell lines with near normal
RT   genotype and phenotype.";
RL   Am. J. Pathol. 157:1623-1631(2000).
//