ID   D1 [Mouse thymocyte]
AC   CVCL_S911
DR   Wikidata; Q54817154
RX   PubMed=10588730;
RX   PubMed=12609543;
WW   Info; COPE; -; http://www.cells-talk.com/index.php/page/copelibrary?key=D1
CC   Characteristics: IL7 dependent. Withdrawal of IL7 induces arrest in G1 phase of the cell cycle, followed by apoptosis (PubMed=12609543).
CC   Characteristics: Does not express CD4 and CD8 (PubMed=12609543).
CC   Knockout cell: Method=KO mouse; MGI; MGI:98834; Trp53.
CC   Derived from site: In situ; Thymus; UBERON=UBERON_0002370.
CC   Cell type: Thymocyte; CL=CL_0000893.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   Age unspecified
CA   Factor-dependent cell line
DT   Created: 03-02-14; Last updated: 10-04-25; Version: 11
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RX   PubMed=10588730; DOI=10.1073/pnas.96.25.14476; PMCID=PMC24461;
RA   Khaled A.R., Kim K., Hofmeister R., Muegge K., Durum S.K.;
RT   "Withdrawal of IL-7 induces Bax translocation from cytosol to
RT   mitochondria through a rise in intracellular pH.";
RL   Proc. Natl. Acad. Sci. U.S.A. 96:14476-14481(1999).
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RX   PubMed=12609543; DOI=10.1016/S0022-1759(02)00513-6;
RA   Kim K., Khaled A.R., Reynolds D., Young H.A., Lee C.-K., Durum S.K.;
RT   "Characterization of an interleukin-7-dependent thymic cell line
RT   derived from a p53(-/-) mouse.";
RL   J. Immunol. Methods 274:177-184(2003).
//