ID   PNUH-12
AC   CVCL_S889
SY   Pusan National University Hospital-12
DR   cancercelllines; CVCL_S889
DR   Wikidata; Q54947688
RX   CelloPub=CLPUB00003;
RX   CelloPub=CLPUB00626;
RX   PubMed=15886465;
RX   PubMed=17923759;
CC   Population: Korean.
CC   Doubling time: 48 hours (CelloPub=CLPUB00003).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser241Cys (c.722C>G); ClinVar=VCV000177791; Zygosity=Unspecified (CelloPub=CLPUB00003).
CC   Derived from site: In situ; Pharynx, hypopharynx; UBERON=UBERON_0001051.
DI   NCIt; C4043; Hypopharyngeal squamous cell carcinoma
DI   ORDO; Orphanet_494547; Squamous cell carcinoma of the hypopharynx
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 19-12-24; Version: 15
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RX   CelloPub=CLPUB00003;
RA   Roh H.-J., Goh E.-K., Wang S.-G., Chon K.-M., Kim Y.-S., Han J.-Y.;
RT   "Establishment and characterization of a novel cell line (PNUH-12)
RT   derived from a human squamous cell carcinoma of the hypopharynx.";
RL   Korean J. Otolaryngol. 42:72-81(1999).
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RX   CelloPub=CLPUB00626;
RA   Chon K.-M., Wang S.-G., Lee B.-J., Lee J.-C., Koo H.-J., Kim S.-H.;
RT   "Establishment of cisplatin resistant head and neck cancer cell lines
RT   and cross-resistance of docetaxel.";
RL   Korean J. Otolaryngol. 48:651-655(2005).
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RX   PubMed=15886465; DOI=10.1159/000085769;
RA   Lee B.-J., Chon K.-M., Kim Y.-S., An W.G., Roh H.-J., Goh E.-K.,
RA   Wang S.-G.;
RT   "Effects of cisplatin, 5-fluorouracil, and radiation on cell cycle
RT   regulation and apoptosis in the hypopharyngeal carcinoma cell line.";
RL   Chemotherapy 51:103-110(2005).
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RX   PubMed=17923759; DOI=10.3346/jkms.2007.22.S.S73; PMCID=PMC2694390;
RA   Lee B.-J., Lee B.-H., Wang S.-G., Lee J.-C., Roh H.-J., Goh E.-K.,
RA   Kim C.-M., Jun E.-S.;
RT   "Change of the expression of human telomerase reverse transcriptase
RT   mRNA and human telomerase RNA after cisplatin and 5-fluorouracil
RT   exposure in head and neck squamous cell carcinoma cell lines.";
RL   J. Korean Med. Sci. 22 Suppl. 1:S73-S78(2007).
//