ID   ONS-F11
AC   CVCL_S735
DR   cancercelllines; CVCL_S735
DR   Wikidata; Q54936429
RX   PubMed=22951319;
CC   Population: Japanese.
CC   Selected for resistance to: NCIt; C129643; Cesium-137 gamma radiation.
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Transformant: NCIt; C129643; Cesium-137 gamma radiation.
CC   Derived from site: In situ; Brain; UBERON=UBERON_0000955.
DI   NCIt; C129443; Medulloblastoma, SHH-activated, TP53-wildtype
DI   ORDO; Orphanet_616; Medulloblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1624 ! ONS-76
SX   Female
AG   2Y
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 05-10-23; Version: 16
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RX   PubMed=22951319; DOI=10.1093/jrr/rrs078;
RA   Sun L., Moritake T., Zheng Y.-W., Suzuki K., Gerelchuluun A., Hong Z.-S.,
RA   Zenkoh J., Taniguchi H., Tsuboi K.;
RT   "In vitro stemness characterization of radio-resistant clones isolated
RT   from a medulloblastoma cell line ONS-76.";
RL   J. Radiat. Res. 54:61-69(2013).
//