ID   RB383
AC   CVCL_S626
SY   Rb383; RB 383
DR   GEO; GSM2043880
DR   Wikidata; Q54949308
RX   PubMed=1682862;
RX   PubMed=2090524;
RX   PubMed=2365495;
RX   PubMed=2751270;
RX   PubMed=2917337;
RX   PubMed=4018796;
RX   PubMed=11520568;
RX   PubMed=18036396;
RX   PubMed=25326674;
RX   PubMed=27115612;
RX   PubMed=30584916;
CC   Doubling time: 97 hours (PubMed=25326674).
CC   Sequence variation: Mutation; HGNC; HGNC:9884; RB1; None_reported; -; Zygosity=- (PubMed=30584916).
CC   Omics: Transcriptomics; Microarray.
DI   NCIt; C8714; Unilateral retinoblastoma
DI   ORDO; Orphanet_790; Retinoblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 10-04-25; Version: 14
//
RX   PubMed=1682862; DOI=10.1016/S0161-6420(91)32134-1;
RA   Chan H.S.L., Thorner P.S., Haddad G., Gallie B.L.;
RT   "Multidrug-resistant phenotype in retinoblastoma correlates with
RT   P-glycoprotein expression.";
RL   Ophthalmology 98:1425-1431(1991).
//
RX   PubMed=2090524; DOI=10.1111/j.1432-0436.1990.tb00479.x;
RA   Griegel S., Heise K., Kindler-Rohrborn A., Rajewsky M.F.;
RT   "In vitro differentiation of human retinoblastoma cells into neuronal
RT   phenotypes.";
RL   Differentiation 45:250-257(1990).
//
RX   PubMed=2365495; DOI=10.1002/ijc.2910460123;
RA   Griegel S., Hong C., Frotschl R., Hulser D.F., Greger V.,
RA   Horsthemke B., Rajewsky M.F.;
RT   "Newly established human retinoblastoma cell lines exhibit an
RT   'immortalized' but not an invasive phenotype in vitro.";
RL   Int. J. Cancer 46:125-132(1990).
//
RX   PubMed=2751270;
RA   Chan H.S.L., Canton M.D., Gallie B.L.;
RT   "Chemosensitivity and multidrug resistance to antineoplastic drugs in
RT   retinoblastoma cell lines.";
RL   Anticancer Res. 9:469-474(1989).
//
RX   PubMed=2917337; DOI=10.1016/0165-4608(89)90079-4;
RA   Horsthemke B., Greger V., Becher R., Passarge E.;
RT   "Mechanism of i(6p) formation in retinoblastoma tumor cells.";
RL   Cancer Genet. Cytogenet. 37:95-102(1989).
//
RX   PubMed=4018796; DOI=10.1007/BF00295364;
RA   Squire J.A., Gallie B.L., Phillips R.A.;
RT   "A detailed analysis of chromosomal changes in heritable and
RT   non-heritable retinoblastoma.";
RL   Hum. Genet. 70:291-301(1985).
//
RX   PubMed=11520568; DOI=10.1016/S0165-4608(01)00427-7;
RA   Chen D., Gallie B.L., Squire J.A.;
RT   "Minimal regions of chromosomal imbalance in retinoblastoma detected
RT   by comparative genomic hybridization.";
RL   Cancer Genet. Cytogenet. 129:57-63(2001).
//
RX   PubMed=18036396; DOI=10.1016/j.cancergencyto.2007.08.014;
RA   Paderova J., Orlic-Milacic M., Yoshimoto M., da Cunha Santos G.,
RA   Gallie B.L., Squire J.A.;
RT   "Novel 6p rearrangements and recurrent translocation breakpoints in
RT   retinoblastoma cell lines identified by spectral karyotyping and mBAND
RT   analyses.";
RL   Cancer Genet. Cytogenet. 179:102-111(2007).
//
RX   PubMed=25326674; DOI=10.1007/s00418-014-1285-z;
RA   Busch M.A., Philippeit C., Weise A., Dunker N.;
RT   "Re-characterization of established human retinoblastoma cell lines.";
RL   Histochem. Cell Biol. 143:325-338(2015).
//
RX   PubMed=27115612; DOI=10.1371/journal.pone.0153323; PMCID=PMC4846005;
RA   Kooi I.E., Mol B.M., Massink M.P.G., de Jong M.C., de Graaf P.,
RA   van der Valk P., Meijers-Heijboer H., Kaspers G.J.L., Moll A.C.,
RA   te Riele H., Cloos J., Dorsman J.C.;
RT   "A meta-analysis of retinoblastoma copy numbers refines the list of
RT   possible driver genes involved in tumor progression.";
RL   PLoS ONE 11:e0153323.1-e0153323.20(2016).
//
RX   PubMed=30584916; DOI=10.1016/j.yexcr.2018.12.018;
RA   Schwermer M., Hiber M., Dreesmann S., Rieb A., Theissen J., Herold T.,
RA   Schramm A., Temming P., Steenpass L.;
RT   "Comprehensive characterization of RB1 mutant and MYCN amplified
RT   retinoblastoma cell lines.";
RL   Exp. Cell Res. 375:92-99(2019).
//