AC   CVCL_S509
SY   CR; CR.HS; 17A02 clone H
DR   FCS-free; 122-23-201-3-4-3
DR   FCS-free; 234-23-478-1-4-12
DR   Wikidata; Q54748632
RX   DOI=10.17169/refubium-4684;
RX   Patent=WO2009156155A1;
RX   PubMed=19071186;
RX   PubMed=19531390;
RX   PubMed=25903999;
RX   PubMed=26814192;
CC   Group: Bird cell line.
CC   Group: Serum/protein free medium cell line.
CC   Group: Vaccine production cell line.
CC   From: ProBioGen AG; Berlin; Germany.
CC   Doubling time: 23 hours (PubMed=19531390).
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5 [Note=E1A/E1B].
CC   Derived from site: In situ; Fetal eye, retina; UBERON=UBERON_0003072.
CC   Breed/subspecies: ST4 compact.
OX   NCBI_TaxID=8855; ! Cairina moschata (Muscovy duck)
SX   Sex unspecified
AG   Embryo
CA   Transformed cell line
DT   Created: 03-02-14; Last updated: 05-10-23; Version: 17
RX   DOI=10.17169/refubium-4684;
RA   Ogorek C.;
RT   "Characterization of the N-glycosylation profile of the new avian cell
RT   line AGE1.CR and the modification of fucosylation.";
RL   Thesis PhD (2012), Freien Universitat Berlin, Germany.
RX   Patent=WO2009156155A1;
RA   Sandig V., Jordan I.;
RT   "Cell line for propagation of highly attenuated alphaviruses.";
RL   Patent number WO2009156155A1, 30-Dec-2009.
RX   PubMed=19071186; DOI=10.1016/j.vaccine.2008.11.066;
RA   Jordan I., Vos A., Beilfuss S., Neubert A., Breul S., Sandig V.;
RT   "An avian cell line designed for production of highly attenuated
RT   viruses.";
RL   Vaccine 27:748-756(2009).
RX   PubMed=19531390; DOI=10.1016/j.vaccine.2009.05.083;
RA   Lohr V., Rath A., Genzel Y., Jordan I., Sandig V., Reichl U.;
RT   "New avian suspension cell lines provide production of influenza virus
RT   and MVA in serum-free media: studies on growth, metabolism and virus
RT   propagation.";
RL   Vaccine 27:4975-4982(2009).
RX   PubMed=25903999; DOI=10.1002/biot.201400388;
RA   Genzel Y.;
RT   "Designing cell lines for viral vaccine production: where do we
RT   stand?";
RL   Biotechnol. J. 10:728-740(2015).
RX   PubMed=26814192; DOI=10.1080/03079457.2016.1138280;
RA   Jordan I., John K., Howing K., Lohr V., Penzes Z., Gubucz-Sombor E.,
RA   Fu Y., Gao P., Harder T., Zadori Z., Sandig V.;
RT   "Continuous cell lines from the Muscovy duck as potential replacement
RT   for primary cells in the production of avian vaccines.";
RL   Avian Pathol. 45:137-155(2016).