ID   MSC 80
AC   CVCL_S187
SY   MSC-80; MSC80; Mouse Schwann Cell line 80
DR   PRIDE; PXD000589
DR   Wikidata; Q54906813
RX   Patent=US7001767;
RX   PubMed=1629940;
RX   PubMed=11836421;
RX   PubMed=25894527;
CC   Characteristics: Can be infected in vitro with mouse scrapie prion (PrPSc) and will continue to produce PrPSc after 18 passages and is able to transmit the prion disease to mice.
CC   Doubling time: 17 hours (PubMed=1629940).
CC   Omics: Proteomics; Subcellular; Cell surface.
CC   Derived from site: In situ; Peripheral nervous system, sciatic nerve; UBERON=UBERON_0001322.
CC   Cell type: Schwann cell; CL=CL_0002573.
CC   Breed/subspecies: C57BL/6 x DBA/2.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
CA   Spontaneously immortalized cell line
DT   Created: 05-11-13; Last updated: 10-04-25; Version: 10
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RX   Patent=US7001767;
RA   Blanquet-Grossard F., Cesbron J.-Y., Lemaire-Vieille C., Follet J.;
RT   "Method for in vitro propagation of the agent responsible for
RT   transmissible spongiform encephalopathies.";
RL   Patent number US7001767, 21-Feb-2006.
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RX   PubMed=1629940; DOI=10.1002/jnr.490320103;
RA   Boutry J.-M., Hauw J.-J., Gansmuller A., Di-Bert N., Pouchelet M.,
RA   Baron-Van Evercooren A.;
RT   "Establishment and characterization of a mouse Schwann cell line which
RT   produces myelin in vivo.";
RL   J. Neurosci. Res. 32:15-26(1992).
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RX   PubMed=11836421; DOI=10.1128/JVI.76.5.2434-2439.2002; PMCID=PMC135945;
RA   Follet J., Lemaire-Vieille C., Blanquet-Grossard F.,
RA   Podevin-Dimster V., Lehmann S., Chauvin J.-P., Decavel J.-P., Varea R.,
RA   Grassi J., Fontes M., Cesbron J.-Y.;
RT   "PrP expression and replication by Schwann cells: implications in
RT   prion spreading.";
RL   J. Virol. 76:2434-2439(2002).
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RX   PubMed=25894527; DOI=10.1371/journal.pone.0121314; PMCID=PMC4404347;
RA   Bausch-Fluck D., Hofmann A., Bock T., Frei A.P., Cerciello F.,
RA   Jacobs A., Moest H., Omasits U., Gundry R.L., Yoon C., Schiess R.,
RA   Schmidt A., Mirkowska P., Hartlova A.S., Van Eyk J.E., Bourquin J.-P.,
RA   Aebersold R., Boheler K.R., Zandstra P.W., Wollscheid B.;
RT   "A mass spectrometric-derived cell surface protein atlas.";
RL   PLoS ONE 10:e0121314.1-e0121314.22(2015).
//