ID   OVCAR-3 SimpleCell O-GalNAc
AC   CVCL_S033
SY   OVCAR-3 SimpleCell; OVCAR-3 SC
DR   cancercelllines; CVCL_S033
DR   Wikidata; Q54937006
RX   PubMed=23584533;
CC   Population: Caucasian.
CC   Characteristics: Cell engineered to produce only truncated GalNAc or NeuAc-alpha-2-6-GalNAc O-glycans.
CC   Knockout cell: Method=ZFN; HGNC; HGNC:24338; C1GALT1C1.
CC   Sequence variation: Mutation; HGNC; HGNC:8979; PIK3R1; Simple; c.1746-2A>T; Zygosity=Heterozygous; Note=Splice acceptor mutation (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
DI   NCIt; C105555; High grade ovarian serous adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0465 ! OVCAR-3
SX   Female
AG   60Y
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 19-12-24; Version: 19
//
RX   PubMed=23584533; DOI=10.1038/emboj.2013.79; PMCID=PMC3655468;
RA   Steentoft, Catharina
RA   Vakhrushev, Sergey Y.
RA   Joshi, Hiren Jitendra
RA   Kong, Yun
RA   Vester-Christensen, Malene Bech
RA   Schjoldager, Katrine Ter-Borch Gram
RA   Lavrsen, Kirstine
RA   Dabelsteen, Sally
RA   Pedersen, Nis B.
RA   Marcos-Silva, Lara
RA   Gupta, Ramneek
RA   Bennett, Eric Paul
RA   Mandel, Ulla
RA   Brunak, Soren
RA   Wandall, Hans Heugh
RA   Levery, Steven Bruce
RA   Clausen, Henrik
RT   "Precision mapping of the human O-GalNAc glycoproteome through
RT   SimpleCell technology.";
RL   EMBO J. 32:1478-1488(2013).
//