ID   HEK293-YFV-prM/E-opt
AC   CVCL_RZ86
DR   Wikidata; Q54882461
RX   PubMed=29513845;
CC   Characteristics: Expresses the YFV prM/E proteins and capable of trans-packaging the transcribed RNA of a YFV reporter replicon, thereby generating pseudo-infectious viral particles.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03314; Yellow fever virus (strain 17D vaccine) genome polyprotein (Note=AA 102-778; protein prM + protein E, codons optimized for expression).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0045 ! HEK293
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 14-05-18; Last updated: 14-08-25; Version: 9
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RX   PubMed=29513845; DOI=10.1590/0037-8682-0220-2017;
RA   de Almeida Queiroz, Sabrina Ribeiro
RA   Silva, Jose Valter Joaquim Jr.
RA   da Silva, Andrea Nazare Monteiro Rangel
RA   de Oliveira Carvalho, Amanda Gomes
RA   da Silva Santos, Jefferson Jose
RA   Gil, Laura Helena Vega Gonzales
RT   "Development and characterization of a packaging cell line for
RT   pseudo-infectious yellow fever virus particle generation.";
RL   Rev. Soc. Bras. Med. Trop. 51:66-70(2018).
//