ID   A549-Mx2/EGFP L2A6
AC   CVCL_RX08
SY   A549 L2A6; A549L2A6; L2A6
DR   cancercelllines; CVCL_RX08
DR   Wikidata; Q54607000
RX   PubMed=22373148;
CC   Population: Caucasian.
CC   Biotechnology: Used for a reporter gene assay (RGA) of the human type 1 interferon potency.
CC   Characteristics: Expression of eGFP is under the control of the control of the mouse Mx2 promoter.
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0023 ! A-549
SX   Male
AG   58Y
CA   Cancer cell line
DT   Created: 05-03-18; Last updated: 19-12-24; Version: 12
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RX   PubMed=22373148; DOI=10.1186/1753-6561-5-S8-P4; PMCID=PMC3284889;
RA   Burgi M., Prieto C., Oggero M., Bollati-Fogolin M.,
RA   Etcheverrigaray M., Kratje R.;
RT   "New reporter cell clones to determine the biological activity of
RT   human type I interferons.";
RL   BMC Proc. 5 Suppl. 8:P4-P4(2011).
//