ID   HEp2-Mx2/EGFP L1G5
AC   CVCL_RX05
SY   HEp L1G5; L1G5
DR   Wikidata; Q54882751
RX   PubMed=22373148;
RX   PubMed=27346232;
CC   Problematic cell line: Contaminated. Parent cell line (HEp-2) has been shown to be a HeLa derivative.
CC   Population: African American.
CC   Biotechnology: Used for a reporter gene assay (RGA) of the human type 1 interferon potency (PubMed=27346232).
CC   Characteristics: Expression of eGFP is under the control of the control of the mouse Mx2 promoter (PubMed=27346232).
CC   Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related endocervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1906 ! HEp-2
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 05-03-18; Last updated: 14-08-25; Version: 10
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RX   PubMed=22373148; DOI=10.1186/1753-6561-5-S8-P4; PMCID=PMC3284889;
RA   Burgi, Maria
RA   Prieto, Claudio
RA   Oggero, Marcos
RA   Bollati-Fogolin, Mariela
RA   Etcheverrigaray, Marina
RA   Kratje, Ricardo
RT   "New reporter cell clones to determine the biological activity of
RT   human type I interferons.";
RL   BMC Proc. 5 Suppl. 8:P4-P4(2011).
//
RX   PubMed=27346232; DOI=10.1016/j.jbiotec.2016.06.021;
RA   Burgi, Maria
RA   Zapol'skii, Viktor A.
RA   Hinkelmann, Bettina
RA   Koster, Mario
RA   Kaufmann, Dieter E.
RA   Sasse, Florenz
RA   Hauser, Hansjorg
RA   Etcheverrigaray, Marina
RA   Kratje, Ricardo
RA   Bollati-Fogolin, Mariela
RA   Oggero, Marcos
RT   "Screening and characterization of molecules that modulate the
RT   biological activity of IFNs-I.";
RL   J. Biotechnol. 233:6-16(2016).
//