ID   TF-1/TPO
AC   CVCL_RM06
DR   cancercelllines; CVCL_RM06
DR   Wikidata; Q54972199
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=9096695;
CC   Population: Japanese.
CC   Characteristics: TPO dependent.
CC   Doubling time: 74 +- 5 hours (PubMed=9096695).
CC   Sequence variation: Gene fusion; HGNC; HGNC:15868; ABHD12 + HGNC; HGNC:1537; CBFA2T3; Name(s)=CBFA2T3-ABHD12 (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Pro (c.182A>C); ClinVar=VCV000280409; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ile251Thrfs*94 (c.752delT); ClinVar=VCV001759367; Zygosity=Unspecified (from parent cell line).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C7152; Erythroleukemia
DI   ORDO; Orphanet_318; Acute erythroid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0559 ! TF-1
SX   Male
AG   35Y
CA   Cancer cell line
DT   Created: 05-03-18; Last updated: 19-12-24; Version: 12
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler H.G.;
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
//
RX   PubMed=9096695; DOI=10.1038/sj.leu.2400621;
RA   Drexler H.G., Zaborski M., Quentmeier H.;
RT   "Thrombopoietin supports the continuous growth of cytokine-dependent
RT   human leukemia cell lines.";
RL   Leukemia 11:541-551(1997).
//