ID   Z-HL16C
AC   CVCL_RL03
SY   ZHL16C
DR   Wikidata; Q54995852
RX   PubMed=11503031;
RX   PubMed=17086279;
RX   PubMed=26116706;
WW   https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=26116706). Originally thought to originate from embryonic lung fibroblasts.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00609.
CC   Population: African American.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): PubMed=26116706
ST   Amelogenin: X
ST   CSF1PO: 9,10
ST   D12S391: 20,25
ST   D13S317: 13.3
ST   D16S539: 9,10
ST   D18S51: 16,17
ST   D19S433: 13,14
ST   D21S11: 27,28
ST   D2S1338: 17
ST   D3S1358: 15,18
ST   D5S818: 11,12
ST   D6S1043: 18
ST   D7S820: 8,12
ST   D8S1179: 12,13
ST   FGA: 18,21
ST   Penta D: 8,15
ST   Penta E: 7,17
ST   TH01: 7
ST   TPOX: 8,12
ST   vWA: 16,18
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 05-03-18; Last updated: 05-10-23; Version: 9
//
RX   PubMed=11503031; DOI=10.3760/cma.j.issn.1003-9279.2000.01.017;
RA   Zhao S.-L., Liu Z.-L., Xie R.-N.;
RT   "Establishment and application of Z-HL16C cell line.";
RL   Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 14:73-76(2000).
//
RX   PubMed=17086279; DOI=10.3760/cma.j.issn.1003-9279.2006.03.010;
RA   Chen J.-P., Li J., Zhao S.-L., Tian J.-Y., Ye F.;
RT   "Establishment of Z-HL16C cell line.";
RL   Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 20:232-234(2006).
//
RX   PubMed=26116706; DOI=10.1096/fj.14-266718;
RA   Ye F., Chen C.-G., Qin J., Liu J., Zheng C.-Y.;
RT   "Genetic profiling reveals an alarming rate of cross-contamination
RT   among human cell lines used in China.";
RL   FASEB J. 29:4268-4272(2015).
//