ID   SUM159PT shPARG
AC   CVCL_RA93
SY   shPARG SUM159
DR   cancercelllines; CVCL_RA93
DR   Wikidata; Q54970842
RX   PubMed=29166620;
CC   Group: Triple negative breast cancer (TNBC) cell line.
CC   Knockout cell: Method=shRNA knockdown; HGNC; HGNC:8605; PARG.
CC   Sequence variation: Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012612; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Leu (c.3140A>T); ClinVar=VCV000013653; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val157_Arg158insLeu (c.472_473ins3); Zygosity=Unspecified (from parent cell line).
CC   Omics: Proteomics; PTM; Poly-ADP-ribosylation.
CC   Derived from site: In situ; Breast; UBERON=UBERON_0000310.
DI   NCIt; C5161; Breast pleomorphic carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_5423 ! SUM159PT
SX   Female
AG   71Y
CA   Cancer cell line
DT   Created: 05-03-18; Last updated: 10-04-25; Version: 12
//
RX   PubMed=29166620; DOI=10.1016/j.celrep.2017.10.106; PMCID=PMC5728415;
RA   Zhen, Yuan-Li
RA   Zhang, Ya-Jie
RA   Yu, Yong-Hao
RT   "A cell-line-specific atlas of PARP-mediated protein
RT   Asp/Glu-ADP-ribosylation in breast cancer.";
RL   Cell Rep. 21:2326-2337(2017).
//