ID   MEF3.8/M32
AC   CVCL_R999
SY   MEF3.8 M32; M32
DR   Wikidata; Q54905033
RX   PubMed=10485464;
RX   PubMed=11956086;
CC   Knockout cell: Method=KO mouse; MGI; MGI:97570; Abcb1a.
CC   Knockout cell: Method=KO mouse; MGI; MGI:97568; Abcb1b.
CC   Knockout cell: Method=KO mouse; MGI; MGI:102676; Abcc1.
CC   Selected for resistance to: ChEBI; CHEBI_50729; Mitoxantrone.
CC   Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_R997 ! MEF3.8
SX   Sex unspecified
AG   Embryo
CA   Spontaneously immortalized cell line
DT   Created: 05-11-13; Last updated: 19-12-24; Version: 8
//
RX   PubMed=10485464;
RA   Allen, John D.
RA   Brinkhuis, Remco F.
RA   Wijnholds, Jan
RA   Schinkel, Alfred H.
RT   "The mouse Bcrp1/Mxr/Abcp gene: amplification and overexpression in
RT   cell lines selected for resistance to topotecan, mitoxantrone, or
RT   doxorubicin.";
RL   Cancer Res. 59:4237-4241(1999).
//
RX   PubMed=11956086;
RA   Allen, John D.
RA   Jackson, Sonja C.
RA   Schinkel, Alfred H.
RT   "A mutation hot spot in the Bcrp1 (Abcg2) multidrug transporter in
RT   mouse cell lines selected for doxorubicin resistance.";
RL   Cancer Res. 62:2294-2299(2002).
//