ID   2L1
AC   CVCL_QW59
DR   cancercelllines; CVCL_QW59
DR   Wikidata; Q54584593
RX   PubMed=9616138;
RX   PubMed=14671638;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg306Ter (c.916C>T); ClinVar=VCV000142144; Zygosity=Unspecified; Note=Germline (PubMed=9616138).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C8252; Therapy-related acute myeloid leukemia
DI   ORDO; Orphanet_86846; Therapy related acute myeloid leukemia and myelodysplastic syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   4Y
CA   Cancer cell line
DT   Created: 15-11-17; Last updated: 19-12-24; Version: 12
//
RX   PubMed=9616138; DOI=10.1182/blood.V91.12.4451;
RA   Felix C.A., Megonigal M.D., Chervinsky D.S., Leonard D.G.B.,
RA   Tsuchida N., Kakati S., Block A.M.W., Fisher J., Grossi M.,
RA   Salhany K.E., Sait S.N.J., Aplan P.D.;
RT   "Association of germline p53 mutation with MLL segmental jumping
RT   translocation in treatment-related leukemia.";
RL   Blood 91:4451-4456(1998).
//
RX   PubMed=14671638; DOI=10.1038/sj.leu.2403236;
RA   Drexler H.G., Quentmeier H., MacLeod R.A.F.;
RT   "Malignant hematopoietic cell lines: in vitro models for the study of
RT   MLL gene alterations.";
RL   Leukemia 18:227-232(2004).
//