ID   NCE-G 84
AC   CVCL_N735
SY   NCE G 84; NCE-G84; G-84; G84; NeuroChirurgie Eppendorf-Glioma 84
DR   EFO; EFO_0006411
DR   ArrayExpress; E-MTAB-2706
DR   BioSample; SAMN03471545
DR   EGA; EGAS00001000610
DR   IARC_TP53; 21612
DR   PharmacoDB; G84_393_2019
DR   Wikidata; Q54907690
RX   PubMed=8289093;
RX   PubMed=15816541;
RX   PubMed=16696057;
RX   PubMed=25485619;
RX   PubMed=25877200;
RX   PubMed=26589293;
CC   HLA typing: A*03:01,30:01; B*08:01,51:01; C*07:01,15:02 (PubMed=26589293).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ala79Val (c.236C>T); Zygosity=Unspecified (PubMed=15816541).
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; SNP array analysis.
CC   Derived from site: In situ; Brain; UBERON=UBERON_0000955.
ST   Source(s): PubMed=25877200
ST   Amelogenin: X
ST   CSF1PO: 11,13
ST   D13S317: 12
ST   D16S539: 11
ST   D18S51: 19
ST   D21S11: 29
ST   D3S1358: 16
ST   D5S818: 11,13
ST   D7S820: 12
ST   D8S1179: 13,14
ST   FGA: 21
ST   Penta D: 12,13
ST   Penta E: 12
ST   TH01: 9.3
ST   TPOX: 8
ST   vWA: 17
DI   NCIt; C9477; Anaplastic astrocytoma
DI   ORDO; Orphanet_251589; Anaplastic astrocytoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 10-04-25; Version: 20
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RX   PubMed=8289093; DOI=10.1007/BF01324703;
RA   Hamel W., Westphal M., Shepard H.M.;
RT   "Loss in expression of the retinoblastoma gene product in human
RT   gliomas is associated with advanced disease.";
RL   J. Neurooncol. 16:159-165(1993).
//
RX   PubMed=15816541;
RA   Kim E.L., Yoshizato K., Kluwe L., Meissner H., Warnecke G., Zapf S.,
RA   Westphal M., Deppert W., Giese A.;
RT   "Comparative assessment of the functional p53 status in glioma
RT   cells.";
RL   Anticancer Res. 25:213-224(2005).
//
RX   PubMed=16696057; DOI=10.1136/mp.49.2.M91; PMCID=PMC408028;
RA   Li W.-X., Martinerie C., Zumkeller W., Westphal M., Perbal B.;
RT   "Differential expression of novH and CTGF in human glioma cell
RT   lines.";
RL   Clin. Mol. Pathol. 49:M91-M97(1996).
//
RX   PubMed=25485619; DOI=10.1038/nbt.3080;
RA   Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S.,
RA   Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G.,
RA   Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J.,
RA   Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L.,
RA   Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J.,
RA   Settleman J., Seshagiri S., Zhang Z.-M.;
RT   "A comprehensive transcriptional portrait of human cancer cell
RT   lines.";
RL   Nat. Biotechnol. 33:306-312(2015).
//
RX   PubMed=25877200; DOI=10.1038/nature14397;
RA   Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M.,
RA   Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S.,
RA   Neve R.M.;
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).
//
RX   PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878;
RA   Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P.,
RA   Loewer M., Sahin U., Castle J.C.;
RT   "TCLP: an online cancer cell line catalogue integrating HLA type,
RT   predicted neo-epitopes, virus and gene expression.";
RL   Genome Med. 7:118.1-118.7(2015).
//