ID   SACHI
AC   CVCL_M501
DR   Cosmic; 2081406
DR   Wikidata; Q54952054
RX   PubMed=11429052;
RX   PubMed=12810253;
RX   PubMed=12886255;
RX   PubMed=17229644;
RX   PubMed=17692805;
RX   PubMed=18647998;
WW   https://www.keatslab.org/myeloma-cell-lines/hmcl-characteristics
CC   Population: Japanese.
CC   Omics: Array-based CGH.
CC   Derived from site: Metastatic; Pericardial effusion; UBERON=UBERON_0002409.
DI   NCIt; C3242; Plasma cell myeloma
DI   ORDO; Orphanet_29073; Multiple myeloma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   47Y
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 29-06-23; Version: 12
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RX   PubMed=11429052; DOI=10.1111/j.1349-7006.2001.tb01142.x;
RA   Hanamura I., Iida S., Akano Y., Hayami Y., Kato M., Miura K.,
RA   Harada S., Banno S., Wakita A., Kiyoi H., Naoe T., Shimizu S.,
RA   Sonta S.-i., Nitta M., Taniwaki M., Ueda R.;
RT   "Ectopic expression of MAFB gene in human myeloma cells carrying
RT   (14;20)(q32;q11) chromosomal translocations.";
RL   Jpn. J. Cancer Res. 92:638-644(2001).
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RX   PubMed=12810253; DOI=10.1016/S0165-4608(02)00862-2;
RA   Ohbayashi K., Taniwaki M., Ninomiya M., Kiyoi H., Iida S., Ueda R.,
RA   Naoe T.;
RT   "A xeno-transplantable plasma cell leukemia line with a split
RT   translocation of the IgH gene.";
RL   Cancer Genet. Cytogenet. 144:31-35(2003).
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RX   PubMed=12886255; DOI=10.1038/sj.leu.2403026;
RA   Hayami Y., Iida S., Nakazawa N., Hanamura I., Kato M., Komatsu H.,
RA   Miura I., Dave B.J., Sanger W.G., Lim B., Taniwaki M., Ueda R.;
RT   "Inactivation of the E3/LAPTm5 gene by chromosomal rearrangement and
RT   DNA methylation in human multiple myeloma.";
RL   Leukemia 17:1650-1657(2003).
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RX   PubMed=17229644; DOI=10.3324/haematol.10300;
RA   Sanda T., Iida S., Kayukawa S., Ueda R.;
RT   "Induction of class II major histocompatibility complex expression in
RT   human multiple myeloma cells by retinoid.";
RL   Haematologica 92:115-120(2007).
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RX   PubMed=17692805; DOI=10.1016/j.ccr.2007.07.003;
RA   Keats J.J., Fonseca R., Chesi M., Schop R., Baker A., Chng W.-J.,
RA   Van Wier S., Tiedemann R., Shi C.-X., Sebag M., Braggio E., Henry T.,
RA   Zhu Y.-X., Fogle H., Price-Troska T.L., Ahmann G.J., Mancini C.,
RA   Brents L.A., Kumar S.K., Greipp P., Dispenzieri A., Bryant B.,
RA   Mulligan G., Bruhn L., Barrett M.T., Valdez R., Trent J.M.,
RA   Stewart A.K., Carpten J.D., Bergsagel P.L.;
RT   "Promiscuous mutations activate the noncanonical NF-kappaB pathway in
RT   multiple myeloma.";
RL   Cancer Cell 12:131-144(2007).
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RX   PubMed=18647998; DOI=10.1093/jncimonographs/lgn011;
RA   Dib A., Gabrea A., Glebov O.K., Bergsagel P.L., Kuehl W.M.;
RT   "Characterization of MYC translocations in multiple myeloma cell
RT   lines.";
RL   J. Natl. Cancer Inst. Monogr. 39:25-31(2008).
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