ID   I-45
AC   CVCL_M200
SY   1-45
DR   Wikidata; Q54897073
RX   PubMed=8010779;
RX   PubMed=8174104;
RX   PubMed=12063468;
RX   PubMed=20482802;
CC   From: Testa, Joseph R.; Fox Chase Cancer Center; Philadelphia; USA.
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=12063468; PubMed=20482802).
DI   NCIt; C45663; Pleural sarcomatoid mesothelioma
DI   ORDO; Orphanet_50251; Pleural mesothelioma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 06-05-13; Last updated: 19-12-24; Version: 11
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RX   PubMed=8010779; DOI=10.1016/0003-4975(94)90090-6;
RA   Smythe W.R., Kaiser L.R., Hwang H.C., Amin K.M., Pilewski J.M.,
RA   Eck S.L., Wilson J.M., Albelda S.M.;
RT   "Successful adenovirus-mediated gene transfer in an in vivo model of
RT   human malignant mesothelioma.";
RL   Ann. Thorac. Surg. 57:1395-1401(1994).
//
RX   PubMed=8174104;
RA   Smythe W.R., Hwang H.C., Amin K.M., Eck S.L., Davidson B.L.,
RA   Wilson J.M., Kaiser L.R., Albelda S.M.;
RT   "Use of recombinant adenovirus to transfer the herpes simplex virus
RT   thymidine kinase (HSVtk) gene to thoracic neoplasms: an effective in
RT   vitro drug sensitization system.";
RL   Cancer Res. 54:2055-2059(1994).
//
RX   PubMed=12063468; DOI=10.1067/mtc.2002.121684;
RA   Smythe W.R., Mohuiddin I., Ozveran M., Cao X.-B.;
RT   "Antisense therapy for malignant mesothelioma with oligonucleotides
RT   targeting the bcl-xl gene product.";
RL   J. Thorac. Cardiovasc. Surg. 123:1191-1198(2002).
//
RX   PubMed=20482802; DOI=10.1186/1476-4598-9-110; PMCID=PMC2882347;
RA   Zhang L.-D., Littlejohn J.E., Cui Y., Cao X.-B., Peddaboina C.,
RA   Smythe W.R.;
RT   "Characterization of bortezomib-adapted I-45 mesothelioma cells.";
RL   Mol. Cancer 9:110.1-110.9(2010).
//