ID   HLF-R10
AC   CVCL_M180
DR   cancercelllines; CVCL_M180
DR   Wikidata; Q54889853
RX   PubMed=22179686;
CC   Population: Japanese.
CC   Selected for resistance to: ChEBI; CHEBI_46345; 5-fluorouracil (5-FU).
CC   Sequence variation: Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly244Ala (c.731G>C); ClinVar=VCV000458560; Zygosity=Unspecified (from parent cell line).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Cell type: Fibroblast; CL=CL_0000057.
DI   NCIt; C7956; Adult hepatocellular carcinoma
DI   ORDO; Orphanet_210159; Adult hepatocellular carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_2947 ! HLF
SX   Male
AG   68Y
CA   Cancer cell line
DT   Created: 06-05-13; Last updated: 19-12-24; Version: 16
//
RX   PubMed=22179686; DOI=10.3892/ijo.2011.1300; PMCID=PMC3584526;
RA   Uchibori K., Kasamatsu A., Sunaga M., Yokota S., Sakurada T.,
RA   Kobayashi E., Yoshikawa M., Uzawa K., Ueda S., Tanzawa H., Sato N.;
RT   "Establishment and characterization of two 5-fluorouracil-resistant
RT   hepatocellular carcinoma cell lines.";
RL   Int. J. Oncol. 40:1005-1010(2012).
//