ID   HKCI-2
AC   CVCL_M173
DR   EGA; EGAD00001004475
DR   Wikidata; Q54889752
RX   DOI=10.1385/CP:1:3-4:313;
RX   PubMed=11793441;
RX   PubMed=15645427;
RX   PubMed=15709204;
RX   PubMed=15765123;
RX   PubMed=19003983;
CC   Population: Chinese.
CC   Karyotypic information: Has lost chromosome Y.
CC   Omics: Transcriptomics; Microarray.
DI   NCIt; C7956; Adult hepatocellular carcinoma
DI   ORDO; Orphanet_210159; Adult hepatocellular carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Adult
CA   Cancer cell line
DT   Created: 06-05-13; Last updated: 10-04-25; Version: 12
//
RX   DOI=10.1385/CP:1:3-4:313;
RA   Pang R.T.-K., Poon T.C.-W., Wong N., Lai P.B.-S., Wong N.L.-Y.,
RA   Chan C.M.-L., Yu J.W.S., Chan A.T.-C., Sung J.J.-Y.;
RT   "Comparison of protein expression patterns between hepatocellular
RT   carcinoma cell lines and a hepatoblastoma cell line.";
RL   Clin. Proteomics 1:313-331(2004).
//
RX   PubMed=11793441; DOI=10.1002/gcc.1220;
RA   Pang E., Wong N., Lai P.B.-S., To K.-F., Lau J.W.-Y., Johnson P.J.;
RT   "Consistent chromosome 10 rearrangements in four newly established
RT   human hepatocellular carcinoma cell lines.";
RL   Genes Chromosomes Cancer 33:150-159(2002).
//
RX   PubMed=15645427; DOI=10.1002/ijc.20684;
RA   Chan K.Y.-Y., Wong N., Lai P.B.-S., Squire J.A., Macgregor P.F.,
RA   Beheshti B., Albert M., To K.-F., Johnson P.J.;
RT   "Transcriptional profiling on chromosome 19p indicated frequent
RT   downregulation of ACP5 expression in hepatocellular carcinoma.";
RL   Int. J. Cancer 114:902-908(2005).
//
RX   PubMed=15709204; DOI=10.1158/1078-0432.1319.11.3;
RA   Wong N., Chan K.Y.-Y., Macgregor P.F., Lai P.B.-S., Squire J.A.,
RA   Beheshti B., Albert M., Leung T.W.-T.;
RT   "Transcriptional profiling identifies gene expression changes
RT   associated with IFN-alpha tolerance in hepatitis C-related
RT   hepatocellular carcinoma cells.";
RL   Clin. Cancer Res. 11:1319-1326(2005).
//
RX   PubMed=15765123; DOI=10.1038/labinvest.3700254;
RA   Pang E., Hu Y., Chan K.Y.-Y., Lai P.B.-S., Squire J.A., Macgregor P.F.,
RA   Beheshti B., Albert M., Leung T.W.-T., Wong N.;
RT   "Karyotypic imbalances and differential gene expressions in the
RT   acquired doxorubicin resistance of hepatocellular carcinoma cells.";
RL   Lab. Invest. 85:664-674(2005).
//
RX   PubMed=19003983; DOI=10.1002/ijc.23968;
RA   Wong N., Yeo W., Wong W.-L., Wong N.L.-Y., Chan K.Y.-Y., Mo F.K.-F.,
RA   Koh J., Chan S.L., Chan A.T.-C., Lai P.B.-S., Ching A.K.-K.,
RA   Tong J.H.-M., Ng H.-K., Johnson P.J., To K.-F.;
RT   "TOP2A overexpression in hepatocellular carcinoma correlates with
RT   early age onset, shorter patients survival and chemoresistance.";
RL   Int. J. Cancer 124:644-652(2009).
//