ID   LuKII
AC   CVCL_LK86
SY   Luk II
DR   Wikidata; Q54903260
RX   PubMed=3863119;
RX   PubMed=6160588;
RX   PubMed=6193516;
CC   Problematic cell line: Misidentified. Originally thought to derive from RPMI-8866 but, based on differences in phosphoglucomutase-1 isozyme fingerprints, was determined not to be originating from that cell line (PubMed=6160588).
CC   Characteristics: Produces TNF.
CC   Cell type: B-cell; CL=CL_0000236.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Transformed cell line
DT   Created: 15-11-17; Last updated: 29-06-23; Version: 6
//
RX   PubMed=3863119; DOI=10.1073/pnas.82.19.6637; PMCID=PMC391265;
RA   Rubin, Berish Y.
RA   Anderson, Sylvia L.
RA   Sullivan, Susan A.
RA   Williamson, Barbara D.
RA   Carswell, Elizabeth Ann
RA   Old, Lloyd John
RT   "Purification and characterization of a human tumor necrosis factor
RT   from the LuKII cell line.";
RL   Proc. Natl. Acad. Sci. U.S.A. 82:6637-6641(1985).
//
RX   PubMed=6193516; DOI=10.1073/pnas.80.17.5397; PMCID=PMC384263;
RA   Williamson, Barbara D.
RA   Carswell, Elizabeth Ann
RA   Rubin, Berish Y.
RA   Prendergast, Jay Scott
RA   Old, Lloyd John
RT   "Human tumor necrosis factor produced by human B-cell lines:
RT   synergistic cytotoxic interaction with human interferon.";
RL   Proc. Natl. Acad. Sci. U.S.A. 80:5397-5401(1983).
//
RX   PubMed=6160588; DOI=10.1073/pnas.77.10.5938; PMCID=PMC350187;
RA   Pickering, Lulu A.
RA   Kronenberg, Lee H.
RA   Stewart, William E. 2nd
RT   "Spontaneous production of human interferon.";
RL   Proc. Natl. Acad. Sci. U.S.A. 77:5938-5942(1980).
//