ID   tsET24
AC   CVCL_LJ52
SY   ts ET24; ET24
DR   Wikidata; Q54973119
RX   PubMed=9251028;
RX   PubMed=12944373;
RX   PubMed=15383328;
CC   Characteristics: Temperature sensitive. At the non-permissive temperature of 39.5 Celsius, this cell line is arrested in the G1-phase and survives for more than 3 days.
CC   Sequence variation: Mutation; UniProtKB; Q8K5D5; Ddx3x; Simple; p.Pro267Ser (c.799C>T); Zygosity=Unspecified (PubMed=12944373).
CC   Transformant: ChEBI; CHEBI_21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=10036; ! Mesocricetus auratus (Golden hamster)
HI   CVCL_1915 ! BHK-21 clone 13
SX   Male
AG   1D
CA   Spontaneously immortalized cell line
DT   Created: 15-11-17; Last updated: 19-12-24; Version: 8
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RX   PubMed=9251028; DOI=10.1016/S0076-6879(97)83024-8;
RA   Nishimoto T.;
RT   "Isolation and characterization of temperature-sensitive mammalian
RT   cell cycle mutants.";
RL   Methods Enzymol. 283:292-309(1997).
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RX   PubMed=12944373; DOI=10.1093/jb/mvg126;
RA   Fukumura J., Noguchi E., Sekiguchi T., Nishimoto T.;
RT   "A temperature-sensitive mutant of the mammalian RNA helicase,
RT   DEAD-BOX X isoform, DBX, defective in the transition from G1 to S
RT   phase.";
RL   J. Biochem. 134:71-82(2003).
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RX   PubMed=15383328; DOI=10.1016/j.yexcr.2004.07.005;
RA   Sekiguchi T., Iida H., Fukumura J., Nishimoto T.;
RT   "Human DDX3Y, the Y-encoded isoform of RNA helicase DDX3, rescues a
RT   hamster temperature-sensitive ET24 mutant cell line with a DDX3X
RT   mutation.";
RL   Exp. Cell Res. 300:213-222(2004).
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