ID   ciPTEC-OAT3
AC   CVCL_LI02
DR   Wikidata; Q54813370
RX   PubMed=26821801;
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:10972; SLC22A8.
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
CC   Derived from site: In situ; Kidney, proximal tubule; UBERON=UBERON_0004134.
CC   Cell type: Epithelial cell of proximal tubule; CL=CL_0002306.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_W184 ! ciPTEC
SX   Female
AG   12Y
CA   Conditionally immortalized cell line
DT   Created: 15-11-17; Last updated: 10-04-25; Version: 11
//
RX   PubMed=26821801; DOI=10.1208/s12248-016-9871-8; PMCID=PMC4779111;
RA   Nieskens T.T.G., Peters J.G.P., Schreurs M.J., Smits N., Woestenenk R.,
RA   Jansen K., van der Made T.K., Roring M., Hilgendorf C., Wilmer M.J.,
RA   Masereeuw R.;
RT   "A human renal proximal tubule cell line with stable organic anion
RT   transporter 1 and 3 expression predictive for antiviral-induced
RT   toxicity.";
RL   AAPS J. 18:465-475(2016).
//