ID   NIH 3T3/HER2-3(400)
AC   CVCL_LG16
SY   NIH 3T3/HER2-3 400; NIH 3T3/HER2-3400
DR   Wikidata; Q54930583
RX   PubMed=1689212;
RX   PubMed=2566907;
RX   PubMed=2890160;
CC   Characteristics: Transfected with at least 55 copies of ERBB2 under the control of a SV40 promoter.
CC   Transfected with: HGNC; 3430; ERBB2.
CC   Transfected with: MGI; MGI:94890; Dhfr.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
CC   Breed/subspecies: NIH Swiss.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_0594 ! NIH 3T3
SX   Male
AG   Embryo
CA   Spontaneously immortalized cell line
DT   Created: 15-11-17; Last updated: 29-06-23; Version: 6
//
RX   PubMed=1689212;
RA   Fendly B.M., Winget M., Hudziak R.M., Lipari M.T., Napier M.A.,
RA   Ullrich A.;
RT   "Characterization of murine monoclonal antibodies reactive to either
RT   the human epidermal growth factor receptor or HER2/neu gene product.";
RL   Cancer Res. 50:1550-1558(1990).
//
RX   PubMed=2566907; DOI=10.1128/mcb.9.3.1165-1172.1989;
RA   Hudziak R.M., Lewis Phillips G.D., Winget M., Fendly B.M.,
RA   Shepard H.M., Ullrich A.;
RT   "p185HER2 monoclonal antibody has antiproliferative effects in vitro
RT   and sensitizes human breast tumor cells to tumor necrosis factor.";
RL   Mol. Cell. Biol. 9:1165-1172(1989).
//
RX   PubMed=2890160; DOI=10.1073/pnas.84.20.7159;
RA   Hudziak R.M., Schlessinger J., Ullrich A.;
RT   "Increased expression of the putative growth factor receptor p185HER2
RT   causes transformation and tumorigenesis of NIH 3T3 cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 84:7159-7163(1987).
//