ID   BO2C11
AC   CVCL_LB95
SY   Bo2C11
DR   Wikidata; Q54797916
RX   PubMed=9657749;
CC   Characteristics: Produces a monoclonal antibody that completely inhibits the procoagulant activity of native and activated factor VIII.
CC   Monoclonal antibody isotype: IgG4, kappa.
CC   Monoclonal antibody target: UniProtKB; P00451; Human F8.
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C27146; Hemophilia A
DI   ORDO; Orphanet_98878; Hemophilia A
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   49Y
CA   Transformed cell line
DT   Created: 22-08-17; Last updated: 29-06-23; Version: 6
//
RX   PubMed=9657749; DOI=10.1182/blood.V92.2.496;
RA   Jacquemin, Marc G.
RA   Desqueper, Benoit G.
RA   Benhida, Abdellah
RA   Vander Elst, Luc P.
RA   Hoylaerts, Marc F.
RA   Bakkus, Marleen H.C.
RA   Thielemans, Kris
RA   Arnout, Jef
RA   Peerlinck, Kathelijne
RA   Gilles, Jean-Guy G.
RA   Vermylen, Jos
RA   Saint-Remy, Jean-Marie R.
RT   "Mechanism and kinetics of factor VIII inactivation: study with an
RT   IgG4 monoclonal antibody derived from a hemophilia A patient with
RT   inhibitor.";
RL   Blood 92:496-506(1998).
//