ID   JSQ-3
AC   CVCL_L892
SY   JSQ 3; JSQ3
DR   cancercelllines; CVCL_L892
DR   IARC_TP53; 1690
DR   Wikidata; Q54899071
RX   PubMed=1423286;
RX   PubMed=1574572;
RX   PubMed=2004949;
RX   PubMed=2573646;
RX   PubMed=3182330;
RX   PubMed=3417487;
RX   PubMed=8339273;
RX   PubMed=9054521;
RX   PubMed=17312569;
CC   Characteristics: Radioresistant (PubMed=2004949).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu298Ter (c.892G>T); ClinVar=VCV000093323; Zygosity=Unspecified (PubMed=1423286; PubMed=8339273).
CC   Derived from site: In situ; Nose, nasal cavity, nasal vestibule; UBERON=UBERON_0000402.
DI   NCIt; C8192; Nasal cavity squamous cell carcinoma
DI   ORDO; Orphanet_500464; Squamous cell carcinoma of the nasal cavity and paranasal sinuses
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 06-05-13; Last updated: 19-12-24; Version: 17
//
RX   PubMed=1423286;
RA   Jung M., Notario V., Dritschilo A.;
RT   "Mutations in the p53 gene in radiation-sensitive and -resistant human
RT   squamous carcinoma cells.";
RL   Cancer Res. 52:6390-6393(1992).
//
RX   PubMed=1574572; DOI=10.2307/3578273;
RA   Dunphy E.J., Beckett M.A., Thompson L.H., Weichselbaum R.R.;
RT   "Expression of the polymorphic human DNA repair gene XRCC1 does not
RT   correlate with radiosensitivity in the cells of human head and neck
RT   tumor cell lines.";
RL   Radiat. Res. 130:166-170(1992).
//
RX   PubMed=2004949; DOI=10.1016/0360-3016(91)90016-W;
RA   Quiet C.A., Weichselbaum R.R., Grdina D.J.;
RT   "Variation in radiation sensitivity during the cell cycle of two human
RT   squamous cell carcinomas.";
RL   Int. J. Radiat. Oncol. Biol. Phys. 20:733-738(1991).
//
RX   PubMed=2573646; DOI=10.1080/09553008914551731;
RA   Weichselbaum R.R., Rotmensch J., Ahmed-Swan S., Beckett M.A.;
RT   "Radiobiological characterization of 53 human tumor cell lines.";
RL   Int. J. Radiat. Biol. 56:553-560(1989).
//
RX   PubMed=3182330; DOI=10.1016/0360-3016(88)90125-3;
RA   Schwartz J.L., Rotmensch J., Giovanazzi S., Cohen M.B.,
RA   Weichselbaum R.R.;
RT   "Faster repair of DNA double-strand breaks in radioresistant human
RT   tumor cells.";
RL   Int. J. Radiat. Oncol. Biol. Phys. 15:907-912(1988).
//
RX   PubMed=3417487; DOI=10.1016/0360-3016(88)90297-0;
RA   Weichselbaum R.R., Beckett M.A., Schwartz J.L., Dritschilo A.;
RT   "Radioresistant tumor cells are present in head and neck carcinomas
RT   that recur after radiotherapy.";
RL   Int. J. Radiat. Oncol. Biol. Phys. 15:575-579(1988).
//
RX   PubMed=8339273;
RA   Brachman D.G., Beckett M.A., Graves D., Haraf D., Vokes E.E.,
RA   Weichselbaum R.R.;
RT   "p53 mutation does not correlate with radiosensitivity in 24 head and
RT   neck cancer cell lines.";
RL   Cancer Res. 53:3667-3669(1993).
//
RX   PubMed=9054521; DOI=10.1089/hum.1997.8.4-467;
RA   Xu L., Pirollo K.F., Chang E.H.-P.;
RT   "Transferrin-liposome-mediated p53 sensitization of squamous cell
RT   carcinoma of the head and neck to radiation in vitro.";
RL   Hum. Gene Ther. 8:467-475(1997).
//
RX   PubMed=17312569; DOI=10.1002/hed.20478;
RA   Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L.,
RA   Koch W.M., Ferris R.L., Lai S.Y.;
RT   "Head and neck squamous cell carcinoma cell lines: established models
RT   and rationale for selection.";
RL   Head Neck 29:163-188(2007).
//