ID   GL-1 [Dog leukemia]
AC   CVCL_L352
DR   Wikidata; Q54835881
RX   PubMed=8741612;
RX   PubMed=22236332;
RX   PubMed=23363222;
RX   PubMed=23365669;
RX   PubMed=24975508;
RX   PubMed=29674676;
CC   Doubling time: 27.3 hours (Note=At 33th passage) (PubMed=8741612).
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; RNAseq.
CC   Omics: Variations; Array-based CGH.
CC   Omics: Variations; CNV analysis.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: B-cell; CL=CL_0000236.
CC   Breed/subspecies: German Shepherd; VBO=VBO_0200577.
DI   NCIt; C128120; Canine leukemia
OX   NCBI_TaxID=9615; ! Canis lupus familiaris (Dog)
SX   Male
AG   9Y
CA   Cancer cell line
DT   Created: 06-05-13; Last updated: 10-04-25; Version: 15
//
RX   PubMed=8741612; DOI=10.1292/jvms.58.469;
RA   Nakaichi M., Taura Y., Kanki M., Mamba K., Momoi Y., Tsujimoto H.,
RA   Nakama S.;
RT   "Establishment and characterization of a new canine B-cell leukemia
RT   cell line.";
RL   J. Vet. Med. Sci. 58:469-471(1996).
//
RX   PubMed=22236332; DOI=10.1111/j.1476-5829.2011.00299.x;
RA   Seiser E.L., Thomas R., Richards K.L., Kelley M.K., Moore P.,
RA   Suter S.E., Breen M.;
RT   "Reading between the lines: molecular characterization of five widely
RT   used canine lymphoid tumour cell lines.";
RL   Vet. Comp. Oncol. 11:30-50(2013).
//
RX   PubMed=23363222; DOI=10.1111/jvp.12039;
RA   Zandvliet M., Teske E., Chapuis T., Fink-Gremmels J., Schrickx J.A.;
RT   "Masitinib reverses doxorubicin resistance in canine lymphoid cells by
RT   inhibiting the function of P-glycoprotein.";
RL   J. Vet. Pharmacol. Ther. 36:583-587(2013).
//
RX   PubMed=23365669; DOI=10.1371/journal.pone.0054464; PMCID=PMC3554772;
RA   Wells J.W., Evans C.H., Scott M.C., Rutgen B.C., O'Brien T.D.,
RA   Modiano J.F., Cvetkovic G., Tepic S.;
RT   "Arginase treatment prevents the recovery of canine lymphoma and
RT   osteosarcoma cells resistant to the toxic effects of prolonged
RT   arginine deprivation.";
RL   PLoS ONE 8:e54464.1-e54464.9(2013).
//
RX   PubMed=24975508; DOI=10.1016/j.tiv.2014.06.004;
RA   Zandvliet M., Teske E., Schrickx J.A.;
RT   "Multi-drug resistance in a canine lymphoid cell line due to increased
RT   P-glycoprotein expression, a potential model for drug-resistant canine
RT   lymphoma.";
RL   Toxicol. In Vitro 28:1498-1506(2014).
//
RX   PubMed=29674676; DOI=10.1038/s41598-018-23207-7; PMCID=PMC5908872;
RA   Taher L., Beck J., Liu W., Roolf C., Soller J.T., Rutgen B.C.,
RA   Hammer S.E., Chodisetti M., Sender S., Sterenczak K.A., Fuellen G.,
RA   Junghanss C., Brenig B., Nolte I., Schutz E., Murua Escobar H.;
RT   "Comparative high-resolution transcriptome sequencing of lymphoma cell
RT   lines and de novo lymphomas reveals cell-line-specific pathway
RT   dysregulation.";
RL   Sci. Rep. 8:6279-6279(2018).
//