ID   OKF6/TERT-2
AC   CVCL_L225
SY   OKF6 Tert 2; OKF6 TERT2
DR   GEO; GSM1431130
DR   Wikidata; Q54931923
RX   PubMed=10648628;
RX   PubMed=21868764;
RX   PubMed=25169794;
WW   Provider; BWH dermatology; -; https://dermatology.bwh.harvard.edu/docs/Cell-Culture-Core-Cell-Lines.pdf
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Variations; Array-based CGH.
CC   Omics: Variations; CNV analysis.
CC   Derived from site: In situ; Oral cavity, floor of mouth; UBERON=UBERON_0003679.
CC   Cell type: Keratinocyte; CL=CL_0000312.
ST   Source(s): PubMed=21868764
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 11
ST   D16S539: 11,12
ST   D5S818: 12,13
ST   D7S820: 8,10
ST   TH01: 6,9.3
ST   TPOX: 9,11
ST   vWA: 14,15
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_L222 ! OKF6
SX   Male
AG   57Y
CA   Telomerase immortalized cell line
DT   Created: 06-05-13; Last updated: 10-04-25; Version: 15
//
RX   PubMed=10648628; DOI=10.1128/mcb.20.4.1436-1447.2000; PMCID=PMC85304;
RA   Dickson M.A., Hahn W.C., Ino Y., Ronfard V., Wu J.Y., Weinberg R.A.,
RA   Louis D.N., Li F.P., Rheinwald J.G.;
RT   "Human keratinocytes that express hTERT and also bypass a
RT   p16(INK4a)-enforced mechanism that limits life span become immortal yet
RT   retain normal growth and differentiation characteristics.";
RL   Mol. Cell. Biol. 20:1436-1447(2000).
//
RX   PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690; PMCID=PMC3229662;
RA   Zhao M., Sano D., Pickering C.R., Jasser S.A., Henderson Y.C.,
RA   Clayman G.L., Sturgis E.M., Ow T.J., Lotan R., Carey T.E., Sacks P.G.,
RA   Grandis J.R., Sidransky D., Heldin N.-E., Myers J.N.;
RT   "Assembly and initial characterization of a panel of 85 genomically
RT   validated cell lines from diverse head and neck tumor sites.";
RL   Clin. Cancer Res. 17:7248-7264(2011).
//
RX   PubMed=25169794; DOI=10.1111/jop.12236;
RA   Dickman C.T.D., Towle R., Saini R., Garnis C.;
RT   "Molecular characterization of immortalized normal and dysplastic oral
RT   cell lines.";
RL   J. Oral Pathol. Med. 44:329-336(2015).
//